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Patent: 10,092,542
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Summary for Patent: 10,092,542
| Title: | Methods of using (+)-2-[1-(3-ethoxy-4-methoxyphenyl)-2-methylsulfonylethyl]-4-acetylaminoi- soindoline-1,3-dione |
| Abstract: | Stereomerically pure (+)-[1-(3-Ethoxy-4-methoxyphenyl)-2-methylsulfonylethyl]-4-acetylaminoiso- indoline-1,3-dione, substantially free of its (-) isomer, and prodrugs, metabolites, polymorphs, salts, solvates, hydrates, and clathrates thereof are discussed. Also discussed are methods of using and pharmaceutical compositions comprising the (+) enantiomer of 2-[1-(3-Ethoxy-4-methoxyphenyl)-2-methylsulfonylethyl]-4-acetylaminoisoin- doline-1,3-dione are disclosed. The methods include methods of treating and/or preventing disorders ameliorated by the reduction of levels of TNF-.alpha. or the inhibition of PDE4. |
| Inventor(s): | Muller; George W. (Rancho Santa Fe, CA), Schafer; Peter H. (Belle Mead, NJ), Man; Hon-Wah (Princeton, NJ), Ge; Chuansheng (Belle Mead, NJ) |
| Assignee: | Celgene Corporation (Summit, NJ) |
| Application Number: | 15/629,678 |
| Patent Claims: | see list of patent claims |
Details for Patent 10,092,542
| Applicant | Tradename | Biologic Ingredient | Dosage Form | BLA | Number | Approval Date | Patent No. | Assignee | Estimated Patent Expiration | Status | Orphan | Source |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Amgen | XGEVA | denosumab | INJECTABLE; SUBCUTANEOUS | 125320 | 002 | 2010-06-01 | Start Trial | Celgene Corporation (Summit, NJ) | 2022-03-20 | RX | Orphan | search |
| Amgen | PROLIA | denosumab | INJECTABLE; SUBCUTANEOUS | 125320 | 001 | 2010-06-01 | Start Trial | Celgene Corporation (Summit, NJ) | 2022-03-20 | RX | Orphan | search |
| >Applicant | >Tradename | >Biologic Ingredient | >Dosage Form | >BLA | >Number | >Approval Date | >Patent No. | >Assignee | >Estimated Patent Expiration | >Status | >Orphan | >Source |
International Patent Family for US Patent 10,092,542
| Country | Patent Number | Estimated Expiration |
|---|---|---|
| South Africa | 200600682 | Start Trial |
| World Intellectual Property Organization (WIPO) | 03080049 | Start Trial |
| United States of America | 10610516 | Start Trial |
| United States of America | 2003187052 | Start Trial |
| United States of America | 2005192336 | Start Trial |
| United States of America | 2005267196 | Start Trial |
| >Country | >Patent Number | >Estimated Expiration |
