DrugPatentWatch Database Preview
Patent: 10,087,237
» See Plans and Pricing
Summary for Patent: 10,087,237
| Title: | Isoform enriched antibody preparation and method for obtaining it |
| Abstract: | Herein is reported a method for producing an antibody preparation comprising the steps of a) applying a buffered solution comprising different isoforms of an antibody to a cation exchange chromatography material, b) applying a first solution with a first conductivity to the cation exchange chromatography material, whereby the antibody isoforms remain bound to the cation exchange chromatography material, and c) applying a second solution with a second conductivity to the cation exchange chromatography material and thereby obtaining the antibody preparation, whereby the conductivity of the second solution exceeds the conductivity of the first solution by not more than 10%. |
| Inventor(s): | Falkenstein; Roberto (Munich, DE), Schwendner; Klaus (Weilheim, DE), Spensberger; Bernhard (Eberfing, DE) |
| Assignee: | F. HOFFMANN-LA ROCHE AG (Nutley, NJ) |
| Application Number: | 14/934,866 |
| Patent Claims: | see list of patent claims |
Details for Patent 10,087,237
| Applicant | Tradename | Biologic Ingredient | Dosage Form | BLA | Number | Approval Date | Patent No. | Assignee | Estimated Patent Expiration | Status | Orphan | Source |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Genentech Inc | HERCEPTIN HYLECTA | trastuzumab; hyaluronidase-oysk | INJECTABLE;SUBCUTANEOUS | 761106 | 001 | 2019-02-28 | Start Trial | F. HOFFMANN-LA ROCHE AG (Nutley, NJ) | 2030-12-21 | RX | search | |
| Genentech | PERJETA | pertuzumab | VIAL; SINGLE-USE | 125409 | 001 | 2012-06-08 | Start Trial | F. HOFFMANN-LA ROCHE AG (Nutley, NJ) | 2030-12-21 | RX | search | |
| Genentech | HERCEPTIN | trastuzumab | VIAL; INTRAVENOUS | 103792 | 001 | 1998-09-25 | Start Trial | F. HOFFMANN-LA ROCHE AG (Nutley, NJ) | 2030-12-21 | RX | Orphan | search |
| >Applicant | >Tradename | >Biologic Ingredient | >Dosage Form | >BLA | >Number | >Approval Date | >Patent No. | >Assignee | >Estimated Patent Expiration | >Status | >Orphan | >Source |
International Patent Family for US Patent 10,087,237
| Country | Patent Number | Estimated Expiration |
|---|---|---|
| World Intellectual Property Organization (WIPO) | 2012084829 | Start Trial |
| United States of America | 2014162317 | Start Trial |
| United States of America | 2017066814 | Start Trial |
| Russian Federation | 2013132405 | Start Trial |
| Russian Federation | 2586515 | Start Trial |
| >Country | >Patent Number | >Estimated Expiration |
