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Last Updated: September 22, 2020

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Patent: 10,083,400

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Summary for Patent: 10,083,400
Title:System and method for providing patient-specific dosing as a function of mathematical models updated to account for an observed patient response
Abstract: A system and method for predicting, proposing and/or evaluating suitable medication dosing regimens for a specific individual as a function of individual-specific characteristics and observed responses of the specific individual. Mathematical models of observed patient responses are used in determining an initial dose. The system and method use the patient\'s observed response to the initial dose to refine the model for use to forecast expected responses to proposed dosing regimens more accurately for a specific patient. More specifically, the system and method uses Bayesian averaging, Bayesian updating and Bayesian forecasting techniques to develop patient-specific dosing regimens as a function of not only generic mathematical models and patient-specific characteristics accounted for in the models as covariate patient factors, but also observed patient-specific responses that are not accounted for within the models themselves, and that reflect variability that distinguishes the specific patient from the typical patient reflected by the model.
Inventor(s): Mould; Diane R. (Fort Myers, FL)
Assignee: Mould; Diane R. (Fort Myers, FL)
Application Number:14/047,545
Patent Claims:see list of patent claims

Details for Patent 10,083,400

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Centocor Inc REMICADE infliximab VIAL 103772 001 1998-08-24   Start Trial Mould; Diane R. (Fort Myers, FL) 2032-10-05 RX Orphan search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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