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Last Updated: October 27, 2020

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Patent: 10,077,447

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Summary for Patent: 10,077,447
Title:Coryneform bacterium and method for producing heterologous fusion proteins
Abstract: The present invention provides a coryneform bacterium having an ability to produce a heterologous fusion protein by secretory production, which has been modified to express a genetic construct for secretory production of the heterologous fusion protein encoding at least a heterologous fusion protein comprising an extein and an intein having an activity of acyl rearrangement. The method for producing proteins modified at the C-terminus is also provided.
Inventor(s): Smirnov; Sergey Vasilievich (Moscow, RU), Kotliarova; Veronika Aleksandrovna (Moscow, RU), Fujii; Hidemi (Kanagawa, JP), Sugiyama; Masakazu (Kanagawa, JP)
Assignee: AJINOMOTO CO., INC. (Tokyo, JP)
Application Number:14/924,201
Patent Claims:see list of patent claims

Details for Patent 10,077,447

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Genentech Inc HERCEPTIN HYLECTA trastuzumab; hyaluronidase-oysk INJECTABLE;SUBCUTANEOUS 761106 001 2019-02-28   Start Trial AJINOMOTO CO., INC. (Tokyo, JP) 2033-04-29 RX search
Genentech HERCEPTIN trastuzumab VIAL; INTRAVENOUS 103792 001 1998-09-25   Start Trial AJINOMOTO CO., INC. (Tokyo, JP) 2033-04-29 RX Orphan search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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