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Last Updated: September 18, 2020

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Patent: 10,077,424

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Summary for Patent: 10,077,424
Title:Methods of producing RPE cells and compositions of RPE cells
Abstract: The present invention provides improved methods for producing RPE cells from human embryonic stem cells or from other human pluripotent stem cells. The invention also relates to human retinal pigmented epithelial cells derived from human embryonic stem cells or other human multipotent or pluripotent stem cells. hRPE cells derived from embryonic stem cells are molecularly distinct from adult and fetal-derived RPE cells, and are also distinct from embryonic stem cells. The hRPE cells described herein are useful for treating retinal degenerative diseases.
Inventor(s): Malcuit; Christopher (Ware, MA), Lemieux; Linda (Hubbardston, MA), Holmes; William (Worcester, MA), Huertas; Pedro (Concord, MA), Vilner; Lucy (Johnston, RI)
Assignee: Astellas Institute for Regenerative Medicine (Marlborough, MA)
Application Number:14/254,833
Patent Claims:see list of patent claims

Details for Patent 10,077,424

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Smith And Nephew SANTYL collagenase OINTMENT;TOPICAL 101995 001 1965-06-04   Start Trial Astellas Institute for Regenerative Medicine (Marlborough, MA) 2027-10-12 RX search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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