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Last Updated: July 29, 2021

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Patent: 10,071,166

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Summary for Patent: 10,071,166
Title:Protein complex using an immunoglobulin fragment and method for the preparation thereof
Abstract: Disclosed are a protein conjugate with improved in vivo duration and stability and the use thereof. The protein conjugate includes a physiologically active polypeptide, a non-peptide polymer and an immunoglobulin Fc fragment. Since the three components are covalently linked, the protein conjugate has extended in vivo duration and enhanced stability for the physiologically active polypeptide. The protein conjugate maintains the in vivo activity at relatively high levels and remarkably increases the serum half-life for the physiologically active polypeptide, with less risk of inducing undesirable immune responses. Thus, the protein conjugate is useful for developing long-acting formulations of various polypeptide drugs.
Inventor(s): Kim; Young Min (Yongin-si, KR), Kim; Dae Jin (Seoul, KR), Bae; Sung Min (Seoul, KR), Lim; Chang Ki (Suwon-si, KR), Kwon; Se Chang (Seoul, KR), Lee; Gwan Sun (Seoul, KR)
Assignee: HANMI SCIENCE CO., LTD. (Hwaseong-si, KR)
Application Number:13/796,135
Patent Claims:see list of patent claims

Details for Patent 10,071,166

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Nps Pharms Inc NATPARA parathyroid hormone INJECTABLE;INJECTION 125511 004 2015-01-23 ⤷  Try it Free HANMI SCIENCE CO., LTD. (Hwaseong-si, KR) 2023-11-13 RX Orphan search
Nps Pharms Inc NATPARA parathyroid hormone INJECTABLE;INJECTION 125511 003 2015-01-23 ⤷  Try it Free HANMI SCIENCE CO., LTD. (Hwaseong-si, KR) 2023-11-13 RX Orphan search
Nps Pharms Inc NATPARA parathyroid hormone INJECTABLE;INJECTION 125511 002 2015-01-23 ⤷  Try it Free HANMI SCIENCE CO., LTD. (Hwaseong-si, KR) 2023-11-13 RX Orphan search
Nps Pharms Inc NATPARA parathyroid hormone INJECTABLE;INJECTION 125511 001 2015-01-23 ⤷  Try it Free HANMI SCIENCE CO., LTD. (Hwaseong-si, KR) 2023-11-13 RX Orphan search
Smith And Nephew SANTYL collagenase OINTMENT;TOPICAL 101995 001 1965-06-04 ⤷  Try it Free HANMI SCIENCE CO., LTD. (Hwaseong-si, KR) 2023-11-13 RX search
Microbix Biosystems KINLYTIC urokinase INJECTABLE;INJECTION 021846 003 1978-01-16 ⤷  Try it Free HANMI SCIENCE CO., LTD. (Hwaseong-si, KR) 2023-11-13 DISCN search
Microbix Biosystems KINLYTIC urokinase INJECTABLE;INJECTION 021846 002 1978-01-16 ⤷  Try it Free HANMI SCIENCE CO., LTD. (Hwaseong-si, KR) 2023-11-13 DISCN search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

International Patent Family for US Patent 10,071,166

Country Patent Number Estimated Expiration
South Africa 201003796 ⤷  Try it Free
World Intellectual Property Organization (WIPO) 2005047334 ⤷  Try it Free
World Intellectual Property Organization (WIPO) 2005047335 ⤷  Try it Free
World Intellectual Property Organization (WIPO) 2005047336 ⤷  Try it Free
World Intellectual Property Organization (WIPO) 2005047337 ⤷  Try it Free
World Intellectual Property Organization (WIPO) 2008136611 ⤷  Try it Free
World Intellectual Property Organization (WIPO) 2009069983 ⤷  Try it Free
>Country >Patent Number >Estimated Expiration

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