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Last Updated: April 24, 2024

Patent: 10,064,948

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Summary for Patent: 10,064,948

Title:	Implantable bio-resorbable polymer charged with fragile macromolecules
Abstract:	The present invention relates to a macromolecule-loaded bioresorbable crosslinked polymer wherein the polymer is obtainable from the polymerization of: (i) at least one monomer of formula (I) (CH.sub.2.dbd.CR.sub.1)CO--K wherein: --K represents O--Z or NH--Z, Z representing (CR.sub.2R.sub.3).sub.m--CH.sub.3, (CH.sub.2--CH.sub.2--O).sub.m--H, (CH.sub.2--CH.sub.2--O).sub.m--CH.sub.3, (CH.sub.2).sub.m--NR.sub.4R.sub.5 with m representing an integer from 1 to 30; --R.sub.1, R.sub.2, R.sub.3, R.sub.4 and R.sub.5 independently represent H or a C1-C6 alkyl; and (ii) at least one bio-resorbable block copolymer cross-linker, and wherein the macromolecule is chosen in the group consisting of proteins and nucleic acids.
Inventor(s):	Moine; Laurence (Saint Cloud, FR), Laurent; Alexandre (Courbevoie, FR), Wassef; Michel (Paris, FR), Bedouet; Laurent (Paris, FR), Louguet; Stephanie (Bordeaux, FR), Verret; Valentin (Gentilly, FR), Servais; Emeline (Janvry, FR)
Assignee:	Occlugel (Jouy en Josas, FR) Centre National de la Recherche Scientifique (CNRS) (Paris, FR) Assistance Publique Hopitaux de Paris (Paris, FR) Universite Paris Diderot--Paris 7 (Paris, FR)
Application Number:	14/003,528
Patent Claims:	see list of patent claims

Details for Patent 10,064,948

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Applicant	Tradename	Biologic Ingredient	Dosage Form	BLA	Approval Date	Patent No.	Expiredate
Janssen Biotech, Inc.	REMICADE	infliximab	For Injection	103772	08/24/1998	⤷ Try a Trial	2031-03-09
Genentech, Inc.	AVASTIN	bevacizumab	Injection	125085	02/26/2004	⤷ Try a Trial	2031-03-09
Kiniksa Pharmaceuticals (uk), Ltd.	ARCALYST	rilonacept	For Injection	125249	02/27/2008	⤷ Try a Trial	2031-03-09
>Applicant	>Tradename	>Biologic Ingredient	>Dosage Form	>BLA	>Approval Date	>Patent No.	>Expiredate

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