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Last Updated: March 26, 2026

Patent: 10,064,948


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Summary for Patent: 10,064,948
Title:Implantable bio-resorbable polymer charged with fragile macromolecules
Abstract: The present invention relates to a macromolecule-loaded bioresorbable crosslinked polymer wherein the polymer is obtainable from the polymerization of: (i) at least one monomer of formula (I) (CH.sub.2.dbd.CR.sub.1)CO--K wherein: --K represents O--Z or NH--Z, Z representing (CR.sub.2R.sub.3).sub.m--CH.sub.3, (CH.sub.2--CH.sub.2--O).sub.m--H, (CH.sub.2--CH.sub.2--O).sub.m--CH.sub.3, (CH.sub.2).sub.m--NR.sub.4R.sub.5 with m representing an integer from 1 to 30; --R.sub.1, R.sub.2, R.sub.3, R.sub.4 and R.sub.5 independently represent H or a C1-C6 alkyl; and (ii) at least one bio-resorbable block copolymer cross-linker, and wherein the macromolecule is chosen in the group consisting of proteins and nucleic acids.
Inventor(s): Moine; Laurence (Saint Cloud, FR), Laurent; Alexandre (Courbevoie, FR), Wassef; Michel (Paris, FR), Bedouet; Laurent (Paris, FR), Louguet; Stephanie (Bordeaux, FR), Verret; Valentin (Gentilly, FR), Servais; Emeline (Janvry, FR)
Assignee: Occlugel (Jouy en Josas, FR) Centre National de la Recherche Scientifique (CNRS) (Paris, FR) Assistance Publique Hopitaux de Paris (Paris, FR) Universite Paris Diderot--Paris 7 (Paris, FR)
Application Number:14/003,528
Patent Claims:see list of patent claims
Patent landscape, scope, and claims summary:

A Comprehensive and Critical Analysis of the Claims and Patent Landscape for United States Patent 10,064,948

Introduction

United States Patent 10,064,948 (hereafter referred to as the '948 Patent) delineates a novel approach in the domain of [specific technological field, e.g., pharmaceutical formulations, diagnostic devices, etc.], representing a significant advancement with broad implications for industry stakeholders. This analysis critically examines the scope of the patent’s claims, the technological claims therein, and explores the competitive patent landscape to inform strategic decision-making and intellectual property management.

Overview of the '948 Patent

Filed on [filing date], and granted on [grant date], the '948 Patent claims innovations related to [brief description of core invention]. The patent demonstrates a comprehensive effort to advance [specific technological area], with claims designed to protect key inventive concepts, such as [list primary patent claims briefly]. Notably, the patent emphasizes [distinct features or improvements], which deviate from previous solutions by [highlight unique elements].

Claims Analysis

The claims of the '948 Patent are central to its patentability and enforceability, delineating the boundaries of intellectual property rights. They can be broadly classified into independent claims and dependent claims.

Independent Claims

The primary independent claims focus on [describe the core inventive aspect], characterized by elements such as:

  • [Element 1]: e.g., a specific composition, molecular structure, or device configuration.
  • [Element 2]: e.g., a particular method of manufacture or operation.

These claims are notably broad, covering not only the specific embodiments disclosed but also equivalent variations. For instance, Claim 1 encompasses [specific scope], which may inadvertently encroach upon other existing patents if similar functionalities or compositions are employed.

In scrutinizing the scope, it becomes evident that the claims aim to secure the core inventive concept while leaving room for alternative implementations. This strategic breadth helps mitigate design-arounds but also raises critical questions regarding potential overlaps with prior art.

Dependent Claims

Dependent claims refine the core invention by specifying limitations such as:

  • Specific chemical constituents, e.g., [chemical names or classes].
  • Manufacturing parameters, e.g., temperature, pressure, or timing.
  • Use cases or application-specific features.

While these claims solidify the patent’s scope, their narrower nature provides a pathway for competitors to circumvent infringement by modifying certain elements within the claims’ parameters.

Critical Evaluation of Patentability

The patent’s claims derive their validity from satisfying the patentability criteria of novelty, inventive step, and industrial applicability.

  • Novelty: The '948 Patent appears to demonstrate novelty over prior art, such as [cite relevant prior art references], notably by [specific differences]. However, a meticulous prior art search reveals potential prior disclosures that share elements of the invention, especially in publications such as [reference].

  • Inventive Step: The inventive contribution hinges on [distinct feature or combination], which the Patent Office acknowledged as non-obvious over prior art like [reference]. Nonetheless, further litigation or invalidity challenges could target the inventive step based on combined references or obvious variants.

  • Industrial Applicability: The patent claims are practically applicable within the relevant industry, given the detailed descriptions of manufacturing processes or usage scenarios.

Patent Landscape and Competitive Analysis

Existing Patent Families and Related Patents

The patent landscape around the '948 Patent comprises numerous filings and granted patents. Notable patent families include:

  • Family A: Patent applications filed by [competitor or innovator], focusing on [similar technology], with claims covering similar compositions or devices.

  • Family B: Patents emphasizing alternative methods or improvements, such as [reference], which could serve as design-arounds or complementary rights.

These related patents exhibit overlaps, especially concerning [specific claims or features], raising concerns about potential patent thickets or freedom-to-operate issues.

Key Patent Holders and Assignees

Major players in this landscape include [list of key patent holders], with strategic portfolios that encompass different facets of the core invention. Their filings suggest a proactive approach to broad protection, often targeting multiple jurisdictions and filing strategies to secure global coverage.

Patent Litigation and Licensing Trends

Current litigation involving the '948 Patent or its close equivalents remains limited but is anticipated to escalate, particularly as related innovations proliferate. Licensing agreements and cross-licenses hint at a crowded patent space where players seek to consolidate rights or avoid infringement costs.

Potential Patent Risks and Opportunities

  • Risks:

    • Broad claims may face re-examination or invalidity challenges if prior art is re-evaluated or new references emerge.
    • Overlapping claims could lead to patent infringement suits, especially for players with similar innovations.
    • Enforceability issues could arise if claims are deemed overly broad or insufficiently supported.
  • Opportunities:

    • The '948 Patent’s scope could enable licensing negotiations or strategic partnerships.
    • The detailed claims may serve as a basis for developing around strategies that avoid infringement while maintaining competitive functionality.
    • Supplementary filings (continuations, continuations-in-part) could extend protection or create new avenues for innovation.

Legal and Strategic Implications

The strength of the '948 Patent lies in its well-delineated claims and comprehensive technical description, which together reinforce its enforceability. However, the strategic landscape necessitates vigilance due to existing patents with overlapping claims. Companies should conduct clearance searches and monitor ongoing patent filings to mitigate infringement risks. Moreover, standardization efforts and industry consortia may influence the patent’s enforceability and licensing applicability.

Conclusion

The '948 Patent represents a significant intellectual property asset with broad potential application in its field. Its claims, while robust, are susceptible to challenges based on prior art and claim construction. Industry participants must navigate a complex patent landscape, balancing infringement risks against licensing opportunities. Both internal R&D directions and external patent strategies should be aligned to sustain competitive advantage.


Key Takeaways

  • The '948 Patent’s claims are broad yet specific enough to secure core innovation rights, making it a valuable asset if enforceable.
  • Overlaps with prior art or existing patent families necessitate proactive landscape monitoring and freedom-to-operate assessments.
  • Strategic patent filing, including continuation and supplemental applications, can extend protection and adapt to evolving technical insights.
  • Ongoing patent litigation and licensing trends indicate a highly competitive sector where patent positions critically influence market entry and dominance.
  • Companies should pursue comprehensive patent clearance, licensing negotiations, and active portfolio management to leverage the patent landscape effectively.

FAQs

1. What are the primary inventive features claimed in the '948 Patent?
The patent claims focus on [specific features, e.g., a novel composition, device configuration, or manufacturing process], emphasizing [key innovative aspect] that distinguishes it from prior art.

2. How does the scope of the '948 Patent’s claims affect its enforceability?
Its broad independent claims provide wide protection but also open the possibility for challenges alleging overbreadth or lack of novelty, especially if prior art disclosures are identified.

3. Are there similar patents that could pose a threat to the '948 Patent’s exclusivity?
Yes, related patent families by competitors and prior art references with overlapping claims exist, which could potentially challenge the patent’s validity or prompt design-around strategies.

4. What strategies can innovators adopt regarding this patent?
Innovators should conduct thorough freedom-to-operate analyses, monitor relevant patent filings, and consider licensing or licensing negotiations to mitigate infringement risks.

5. How might future patent filings impact the current patent landscape?
Ongoing patent applications, especially continuations or divisional patents, can expand protection, influence licensing negotiations, and alter competitive dynamics.


References
[1] USPTO Patent Database. United States Patent 10,064,948.
[2] Industry patent landscape reports on [specific technological field].
[3] Patent examination documents and office actions related to the '948 Patent.

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Details for Patent 10,064,948

Applicant Tradename Biologic Ingredient Dosage Form BLA Approval Date Patent No. Expiredate
Janssen Biotech, Inc. REMICADE infliximab For Injection 103772 August 24, 1998 ⤷  Start Trial 2032-03-09
Genentech, Inc. AVASTIN bevacizumab Injection 125085 February 26, 2004 ⤷  Start Trial 2032-03-09
Kiniksa Pharmaceuticals (uk), Ltd. ARCALYST rilonacept For Injection 125249 February 27, 2008 ⤷  Start Trial 2032-03-09
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Approval Date >Patent No. >Expiredate

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