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Last Updated: September 26, 2022

Patent: 10,064,938


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Summary for Patent: 10,064,938
Title:Localized immunosuppression of allografts for peripheral nerve repair
Abstract: Embodiments described herein relate to restorative solutions for segmental peripheral nerve (PN) defects using allografted PNs for stimulating PN repair. More specifically, embodiments described herein provide for localized immunosuppression (LIS) surrounding PN allografts as an alternative to systemically suppressing a patient\'s entire immune system. Methods include localized release of immunosuppressive (ISV) agents are contemplated in one embodiment. Methods also include localized application of immunosuppressive (ISV) regulatory T-cells (Tregs) in other embodiments. Hydrogel carrier materials for delivery of ISV agents and are also described herein.
Inventor(s): Bushman; Jared (Laramie, WY)
Assignee: UNIVERSITY OF WYOMING (Laramie, WY)
Application Number:15/457,359
Patent Claims:see list of patent claims

Details for Patent 10,064,938

Applicant Tradename Biologic Ingredient Dosage Form BLA Approval Date Patent No. Expiredate
Pharmacia & Upjohn Company Llc ATGAM lymphocyte immune globulin, anti-thymocyte globulin (equine) Injection 103676 12/04/1996 See Plans and Pricing 2036-03-11
Novartis Pharmaceuticals Corporation SIMULECT basiliximab For Injection 103764 05/12/1998 See Plans and Pricing 2036-03-11
Novartis Pharmaceuticals Corporation SIMULECT basiliximab For Injection 103764 01/02/2003 See Plans and Pricing 2036-03-11
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Approval Date >Patent No. >Expiredate

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