Methods for treating cancer by administering humanized pan-HER antibody compositions
The invention relates to humanized recombinant antibodies targeting the EGFR family receptors EGFR, HER2 and HER3, compositions comprising at least one humanized anti-EGFR antibody, at least one humanized anti-HER2 antibody and at least one humanized anti-HER3 antibody, and use of the antibody compositions for treatment of cancer. The invention also relates to the use of antibodies targeting multiple EGFR-family receptors to treat cancer (e.g., pancreatic cancer) and cancer that has acquired resistance to previous therapies.
Lantto; Johan (Lund, SE), Andersen; Kim Vilbour (Bronshoj, DK), Andersen; Peter Sejer (Vanlose, DK), Strandh; Magnus (Malmo, SE), Koefoed; Klaus (Kobenhavn S, DK), Nielsen; Lars Sogaard (Niva, DK), Pedersen; Mikkel Wandahl (Alleroed, DK), Jacobsen; Helle (Virum, DK), Kragh; Michael (Copenhagen, DK), Kjaer; Ida (Copenhagen, DK), Poulsen; Thomas Tuxen (Dyssegaard, DK)
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