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Last Updated: July 24, 2021

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Patent: 10,047,353

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Summary for Patent: 10,047,353
Title:Grimonitia-hollisae-derived recombinant collagenase and enzyme agent for cell and tissue dissociation
Abstract: Recombinant collagenases with a stable specific activity and enzyme agents for cell and tissue dissociation such a recombinant are provided. The recombinant collagenase is derived from Grimontia hollisae-derived collagenase is characterized by having, from the N terminus to the C terminus, a collagenase catalytic domain, a linker region sequence, and a prepeptidase C terminal domain, which Grimontia hollisae-derived recombinant collagenase does not comprise at least the prepeptidase C terminal domain. The obtained recombinant collagenase has a high and stable specific activity.
Inventor(s): Teramura; Naoko (Tokyo, JP), Iijima; Katsumasa (Tokyo, JP), Hayashida; Osamu (Tokyo, JP), Tanaka; Keisuke (Tokyo, JP), Hattori; Shunji (Tokyo, JP), Okitsu; Teru (Tokyo, JP), Takeuchi; Shoji (Tokyo, JP)
Assignee: Nippi, Incorporated (Tokyo, JP) The University of Tokyo (Tokyo, JP)
Application Number:15/123,986
Patent Claims:see list of patent claims

Details for Patent 10,047,353

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Smith And Nephew SANTYL collagenase OINTMENT;TOPICAL 101995 001 1965-06-04 ⤷  Free Forever Trial Nippi, Incorporated (Tokyo, JP) The University of Tokyo (Tokyo, JP) 2034-03-06 RX search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

International Patent Family for US Patent 10,047,353

Country Patent Number Estimated Expiration
World Intellectual Property Organization (WIPO) 2015133636 ⤷  Free Forever Trial
United States of America 2017218352 ⤷  Free Forever Trial
South Korea 20160131037 ⤷  Free Forever Trial
Japan 6661072 ⤷  Free Forever Trial
Japan WO2015133636 ⤷  Free Forever Trial
European Patent Office 3115455 ⤷  Free Forever Trial
China 106164269 ⤷  Free Forever Trial
>Country >Patent Number >Estimated Expiration

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