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Last Updated: September 22, 2020

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Patent: 10,035,817

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Summary for Patent: 10,035,817
Title:Method of purifying cell-binding agent-cytotoxic agent conjugates with a PVDF membrane
Abstract: The invention provides processes for preparing purified cell-binding agent cytotoxic agent conjugates comprising subjecting a mixture comprising a cell-binding agent cytotoxic agent conjugate and one or more impurities to a polyvinyl difluoride (PVDF) membrane to remove at least a portion of the impurities from the mixture, thereby providing a purified cell-binding agent cytotoxic agent conjugate.
Inventor(s): Chen; Xiaoxi Kevin (Natick, MA), Li; Xinfang (Newton, MA)
Assignee: IMMUNOGEN, INC. (Waltham, MA)
Application Number:14/430,701
Patent Claims:see list of patent claims

Details for Patent 10,035,817

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Genentech RITUXAN rituximab SOLUTION;INTRAVENOUS 103705 001 1997-11-26   Start Trial IMMUNOGEN, INC. (Waltham, MA) 2032-10-04 RX search
Genentech RITUXAN rituximab SOLUTION;INTRAVENOUS 103705 002 1997-11-26   Start Trial IMMUNOGEN, INC. (Waltham, MA) 2032-10-04 RX search
Genentech HERCEPTIN trastuzumab VIAL; INTRAVENOUS 103792 001 1998-09-25   Start Trial IMMUNOGEN, INC. (Waltham, MA) 2032-10-04 RX Orphan search
Genentech Inc RITUXAN HYCELA rituximab; hyaluronidase (human recombinant) SOLUTION;SUBCUTANEOUS 761064 001 2017-06-22   Start Trial IMMUNOGEN, INC. (Waltham, MA) 2032-10-04 RX Orphan search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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