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Last Updated: February 1, 2023

Patent: 10,035,817


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Summary for Patent: 10,035,817
Title:Method of purifying cell-binding agent-cytotoxic agent conjugates with a PVDF membrane
Abstract: The invention provides processes for preparing purified cell-binding agent cytotoxic agent conjugates comprising subjecting a mixture comprising a cell-binding agent cytotoxic agent conjugate and one or more impurities to a polyvinyl difluoride (PVDF) membrane to remove at least a portion of the impurities from the mixture, thereby providing a purified cell-binding agent cytotoxic agent conjugate.
Inventor(s): Chen; Xiaoxi Kevin (Natick, MA), Li; Xinfang (Newton, MA)
Assignee: IMMUNOGEN, INC. (Waltham, MA)
Application Number:14/430,701
Patent Claims:see list of patent claims

Details for Patent 10,035,817

Applicant Tradename Biologic Ingredient Dosage Form BLA Approval Date Patent No. Expiredate
Genentech, Inc. RITUXAN rituximab Injection 103705 11/26/1997 See Plans and Pricing 2032-10-04
Genentech, Inc. HERCEPTIN trastuzumab For Injection 103792 09/25/1998 See Plans and Pricing 2032-10-04
Genentech, Inc. HERCEPTIN trastuzumab For Injection 103792 02/10/2017 See Plans and Pricing 2032-10-04
Genentech, Inc. RITUXAN HYCELA rituximab and hyaluronidase human Injection 761064 06/22/2017 See Plans and Pricing 2032-10-04
Genentech, Inc. HERCEPTIN HYLECTA trastuzumab and hyaluronidase-oysk Injection 761106 02/28/2019 See Plans and Pricing 2032-10-04
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Approval Date >Patent No. >Expiredate

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