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Last Updated: September 22, 2020

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Patent: 10,030,238

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Summary for Patent: 10,030,238
Title:Recombinant clostridium botulinum neurotoxins
Abstract: The invention provides a nucleic acid sequence comprising a sequence of contiguous nucleotides, wherein said sequence of contiguous nucleotides has at least 90% sequence identity to the nucleic acid sequence of SEQ ID NO: 1, and wherein said sequence of contiguous nucleotides encodes a single-chain BoNT/E1 protein. The present invention also provides methods for producing soluble single-chain BoNT/E1 protein in an E. coli host cell, together with methods for producing soluble di-chain BoNT/E1 protein.
Inventor(s): Cossins; Aimee (Abingdon, GB), Beard; Matthew (Abingdon, GB), Marks; Philip (Wrexham, GB)
Assignee: IPSEN BIOINNOVATION LIMITED (Abingdon, Oxfordshire, GB) IPSEN BIOPHARM LIMITED (Slough, Berkshire, GB)
Application Number:14/427,234
Patent Claims:see list of patent claims

Details for Patent 10,030,238

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Merck Sharp & Dohme Corp. ZOSTAVAX zoster vaccine live INJECTION, POWDER, LYOPHILIZED, FOR SUSPENSION 125123 001 2006-05-25   Start Trial IPSEN BIOINNOVATION LIMITED (Abingdon, Oxfordshire, GB) IPSEN BIOPHARM LIMITED (Slough, Berkshire, GB) 2032-10-31 search
Merck Sharp & Dohme Corp. ZOSTAVAX zoster vaccine live INJECTION, POWDER, LYOPHILIZED, FOR SUSPENSION 125123 1 2006-05-25   Start Trial IPSEN BIOINNOVATION LIMITED (Abingdon, Oxfordshire, GB) IPSEN BIOPHARM LIMITED (Slough, Berkshire, GB) 2032-10-31 search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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