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Last Updated: February 1, 2023

Patent: 10,028,993

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Summary for Patent: 10,028,993
Title:Method of reducing titers of antibodies specific for a therapeutic agent
Abstract: The present invention relates, in general, to a method of treating patients undergoing enzyme replacement therapy (ERT) or other therapy involving the administration of a proteinaceous therapeutic agent as well gene replacement therapy with non-viral or viral vectors, or other therapeutic modality or modalities, used alone or in combination, which involve the administration of exogenous substances for potential therapeutic benefit, including, but not limited to DNA vaccines, siRNA, splice-site switching oligomers (SSOs) as well as RNA-based nanoparticles (RNPs) and nanovaccines. The invention further relates to compounds and compositions suitable for use in such methods.
Inventor(s): Kishnani; Priya S. (Durham, NC), Banugaria; Suhrad G. (Durham, NC), Koeberl; Dwight D. (Durham, NC), Prater; Sean N. (Durham, NC)
Assignee: Duke University (Durham, NC)
Application Number:15/438,375
Patent Claims:see list of patent claims

Details for Patent 10,028,993

Applicant Tradename Biologic Ingredient Dosage Form BLA Approval Date Patent No. Expiredate
Genentech, Inc. RITUXAN rituximab Injection 103705 11/26/1997 See Plans and Pricing 2030-05-06
Genentech, Inc. RITUXAN HYCELA rituximab and hyaluronidase human Injection 761064 06/22/2017 See Plans and Pricing 2030-05-06
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Approval Date >Patent No. >Expiredate

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