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Last Updated: July 26, 2021

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Patent: 10,012,654

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Summary for Patent: 10,012,654
Title:Biomarkers in inflammatory bowel disease
Abstract: The present invention provides a method of determining whether a patient with inflammatory bowel disease (IBD) and who has been treated with anti TNF.alpha. therapy is in immunological remission (IR), said method comprising determining the level of a cytokine selected from TNF.alpha., IL-17 and IFN-y in a Gl mucosal sample from said patient. Also provided are methods of prognosis and treatment using said method of determination, in particular discontinuing treatment if said patient is in IR and continuing treatment if said patient is not in IR.
Inventor(s): Florholmen; Jon (Tromso, NO), Olsen; Trine (Tromso, NO), Rismo; Renathe (Tromso, NO), Goll; Rasmus (Tromso, NO), Cui; Guanglin (Tromso, NO)
Assignee: UNIVERSITY OF TROMSO (Tromso, NO)
Application Number:14/653,750
Patent Claims:see list of patent claims

Details for Patent 10,012,654

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Janssen Biotech SIMPONI ARIA golimumab INJECTABLE; INJECTION 125433 001 2013-07-18 ⤷  Free Forever Trial UNIVERSITY OF TROMSO (Tromso, NO) 2032-12-21 RX search
Centocor Ortho Biotech Inc SIMPONI golimumab INJECTABLE; INJECTION 125289 001 2009-04-24 ⤷  Free Forever Trial UNIVERSITY OF TROMSO (Tromso, NO) 2032-12-21 RX Orphan search
Abbvie Inc HUMIRA adalimumab VIAL 125057 002 2002-12-31 ⤷  Free Forever Trial UNIVERSITY OF TROMSO (Tromso, NO) 2032-12-21 RX search
Abbvie Inc HUMIRA adalimumab SYRINGE 125057 001 2002-12-31 ⤷  Free Forever Trial UNIVERSITY OF TROMSO (Tromso, NO) 2032-12-21 RX search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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