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Last Updated: September 27, 2020

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Patent: 10,010,508

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Summary for Patent: 10,010,508
Title:MTAB-TA-Coated gold nanorods and method of fabrication
Abstract: 11-mercaptoundecyl trimethylammonium bromide gold nanorod (MTAB-GNR) coated with tannic acid (TA), useful for biological cellular imaging. A method of synthesizing tannic acid-coated 11-mercaptoundecyl trimethylammonium bromide gold nanorods (MTAB-TA GNRs) comprising presenting 11-mercaptoundecyl trimethylammonium bromide gold nanorods (MTAB-GNRs) in solution; functionalizing the MTAB-GNRs with tannic acid (TA) added to the MTAB-GNRs, the tannic acid configured to form a coating around the MTAB-GNRs forming MTAB-TA GNRs. The functionalizing step may further comprise adding a sodium chloride solution to the MTAB-TA GNR solution, and/or adding a MOPS buffer to the solution of tannic acid with MTAB-GNRs, and the tannic acid MTAB-GNR solution may be vortexed after each step. The MTAB-TA GNR solution may be centrifuged to separate the MTAB-TA GNRs from residual tannic acid and supernatant, and sterile water may be added to the MTAB-TA GNR solution and centrifuging performed to remove residual tannic acid from the MTAB-TA GNRs.
Inventor(s): Polito; Anthony B (Springboro, OH), Hussain; Saber M (Beavercreek, OH)
Assignee: The United States of America as represented by the Secretary of the Air Force (Washington, DC)
Application Number:15/379,581
Patent Claims:see list of patent claims

Details for Patent 10,010,508

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Merck Sharp & Dohme Corp. ZOSTAVAX zoster vaccine live INJECTION, POWDER, LYOPHILIZED, FOR SUSPENSION 125123 001 2006-05-25   Start Trial The United States of America as represented by the Secretary of the Air Force (Washington, DC) 2039-09-23 search
Merck Sharp & Dohme Corp. ZOSTAVAX zoster vaccine live INJECTION, POWDER, LYOPHILIZED, FOR SUSPENSION 125123 1 2006-05-25   Start Trial The United States of America as represented by the Secretary of the Air Force (Washington, DC) 2039-09-23 search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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Serving leading biopharmaceutical companies globally:

Colorcon
Harvard Business School
Merck
Johnson and Johnson
Baxter
McKesson

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