Last Updated: November 8, 2026

Patent: 10,010,400

Summary for Patent: 10,010,400

Title:	Devices and methods for local delivery of drug to upper urinary tract
Abstract:	Drug delivery devices include a flexible elongate body having a bladder end portion, a kidney end portion, and a drug lumen extending therebetween; and a drug reservoir which is located at the bladder end portion, contains a drug, and is defined at least in part by a semi-permeable wall. Methods include inserting the device into the ureter of a patient and permitting water in the bladder to diffuse through the semi-permeable wall to create an osmotic pressure to pump the drug through the drug lumen and out of the device at the kidney end portion and into the renal pelvis.
Inventor(s):	Lee; Heejin (Bedford, MA), Larrivee-Elkins; Cheryl (Framingham, MA), Ho Duc; Hong Linh (Weston, MA), Mixter; Colin (Exeter, NH)
Assignee:	TARIS Biomedical LLC (Lexington, MA)
Application Number:	15/085,179
Patent Claims:	see list of patent claims

Details for Patent 10,010,400

Glossary

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Applicant	Tradename	Biologic Ingredient	Dosage Form	BLA	Approval Date	Patent No.	Expiredate
Merck Teknika Llc	TICE BCG	bcg live	For Injection	102821	June 21, 1989	⤷ Start Trial	2036-03-30
Iovance Biotherapeutics Manufacturing Llc	PROLEUKIN	aldesleukin	For Injection	103293	May 5, 1992	⤷ Start Trial	2036-03-30
Genentech, Inc.	AVASTIN	bevacizumab	Injection	125085	February 26, 2004	⤷ Start Trial	2036-03-30
>Applicant	>Tradename	>Biologic Ingredient	>Dosage Form	>BLA	>Approval Date	>Patent No.	>Expiredate

International Patent Family for US Patent 10,010,400

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Country	Patent Number	Estimated Expiration
Denmark	3277363	⤷ Start Trial
European Patent Office	3277363	⤷ Start Trial
Spain	2734394	⤷ Start Trial
Japan	2018516096	⤷ Start Trial
>Country	>Patent Number	>Estimated Expiration

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