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Last Updated: April 19, 2024

Claims for Patent: 9,676,870


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Summary for Patent: 9,676,870
Title:Methods of treating atherosclerosis and aneurysm
Abstract: The technology described herein is directed to methods of treating cardiovascular and metabolic disorders.
Inventor(s): Shi; Guo-Ping (Newton, MA)
Assignee: The Brigham and Women\'s Hospital, Inc. (Boston, MA)
Application Number:14/236,544
Patent Claims:1. A method comprising, administering a therapeutically effective amount of an IgE signaling inhibitor to a subject in need of a treatment for atherosclerosis, wherein the IgE inhibitor binds to IgE and inhibits the binding of IgE to a receptor molecule.

2. A method comprising, administering a therapeutically effective amount of an IgE signaling inhibitor to a subject in need of a treatment for abdominal aortic aneurysm, wherein the IgE inhibitor binds to IgE and inhibits the binding of IgE to a receptor molecule.

3. The method of claim 1, wherein the IgE inhibitor is selected from the group consisting of; an IgE monoclonal antibody; omalizumab; and talizumab.

4. The method of claim 2, wherein the IgE inhibitor is selected from the group consisting of; an anti-IgE monoclonal antibody; omalizumab; and talizumab.

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