Degradable material for use in three dimensional printing and method for preparing the same
A liquid composition for producing a self-destructible temporary structure by additive manufacturing is provided. The liquid composition includes a biosynthetic copolymer as a degradable component and an enzyme as a disintegrating agent, the disintegrating agent is capable of disintegrating the degradable component, wherein after exposure to an external trigger, the disintegrating agent gradually degrades the degradable component.
Dikovsky; Daniel (Rehovot, IL), Napadensky; Eduardo (Netanya, IL)
STRATASYS LTD. (Rehovot, IL)
1. A 3-dimensional self-destructible temporary structure for supporting an object during a layer-by layer printing process, the structure comprising: hydrogel layers,
wherein each hydrogel layer comprises a polymerized copolymer, and enzyme which is capable of disintegrating the polymerized copolymer, wherein the hydrogel layers form a 3-dimensional self-destructible temporary structure.
2. The 3-dimensional self-destructible temporary structure of claim 1, wherein the copolymer comprises a protein or a peptide.
3. The 3-dimensional self-destructible temporary structure of claim 1, wherein the copolymer comprises any one or more of poly(ethyleneglycol) (PEG), poly(acrylic acid), poly(hyaluronic acid), poly(caprolactone) or poly(vinyl alcohol).
4. The 3-dimensional self-destructible temporary structure of claim 1, wherein the enzyme is an esterase, a trypsin, a collagenase, a cellulase or a dextranase.
5. The 3-dimensional self-destructible temporary structure of claim 4, wherein the esterase is lipase.
6. The 3-dimensional self-destructible temporary structure of claim 1 wherein the enzyme is encapsulated by nanoparticles.
7. The 3-dimensional self-destructible temporary structure of claim 1, wherein the layers of self-destructible temporary structure are formed by inkjet printing.
8. The 3-dimensional self-destructible temporary structure of claim 1, wherein the enzyme comprises hydrogel particles that gradually release enzyme by diffusion.
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