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Last Updated: April 25, 2024

Claims for Patent: 9,527,247

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Summary for Patent: 9,527,247

Title:	Degradable material for use in three dimensional printing and method for preparing the same
Abstract:	A liquid composition for producing a self-destructible temporary structure by additive manufacturing is provided. The liquid composition includes a biosynthetic copolymer as a degradable component and an enzyme as a disintegrating agent, the disintegrating agent is capable of disintegrating the degradable component, wherein after exposure to an external trigger, the disintegrating agent gradually degrades the degradable component.
Inventor(s):	Dikovsky; Daniel (Rehovot, IL), Napadensky; Eduardo (Netanya, IL)
Assignee:	STRATASYS LTD. (Rehovot, IL)
Application Number:	13/926,489
Patent Claims:	1. A 3-dimensional self-destructible temporary structure for supporting an object during a layer-by layer printing process, the structure comprising: hydrogel layers, wherein each hydrogel layer comprises a polymerized copolymer, and enzyme which is capable of disintegrating the polymerized copolymer, wherein the hydrogel layers form a 3-dimensional self-destructible temporary structure. 2. The 3-dimensional self-destructible temporary structure of claim 1, wherein the copolymer comprises a protein or a peptide. 3. The 3-dimensional self-destructible temporary structure of claim 1, wherein the copolymer comprises any one or more of poly(ethyleneglycol) (PEG), poly(acrylic acid), poly(hyaluronic acid), poly(caprolactone) or poly(vinyl alcohol). 4. The 3-dimensional self-destructible temporary structure of claim 1, wherein the enzyme is an esterase, a trypsin, a collagenase, a cellulase or a dextranase. 5. The 3-dimensional self-destructible temporary structure of claim 4, wherein the esterase is lipase. 6. The 3-dimensional self-destructible temporary structure of claim 1 wherein the enzyme is encapsulated by nanoparticles. 7. The 3-dimensional self-destructible temporary structure of claim 1, wherein the layers of self-destructible temporary structure are formed by inkjet printing. 8. The 3-dimensional self-destructible temporary structure of claim 1, wherein the enzyme comprises hydrogel particles that gradually release enzyme by diffusion.

Details for Patent 9,527,247

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Applicant	Tradename	Biologic Ingredient	Dosage Form	BLA	Approval Date	Patent No.	Expiredate
Smith & Nephew, Inc.	SANTYL	collagenase	Ointment	101995	06/04/1965	⤷ Try a Trial	2029-06-01
>Applicant	>Tradename	>Biologic Ingredient	>Dosage Form	>BLA	>Approval Date	>Patent No.	>Expiredate

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