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Last Updated: April 19, 2024

Claims for Patent: 9,526,709

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Summary for Patent: 9,526,709

Title:	Compositions and methods for treating cancer
Abstract:	The present invention provides, in part, compositions and methods for treating cancer using a combination of C6-ceramide and other anti-cancer agents.
Inventor(s):	Wanebo; Harold J. (Bristol, RI)
Assignee:	Chemo-Enhanced LLC (Woonsocket, RI)
Application Number:	14/110,318
Patent Claims:	1. A method for treating colorectal cancer having an activating KRAS mutation, comprising administering to a mammal a pharmaceutically acceptable formulation comprising (a) an effective amount of C6-ceramide; (b) an effective amount of 5-fluorouracil; (c) an effective amount of oxaliplatin; and (d) an effective amount of cetuximab. 2. The method of claim 1, wherein the mammal is a human. 3. The method of claim 1, wherein the activating KRAS mutations is a human KRAS polypeptide having a mutation selected from the group consisting of G12C, G12A, G12D, G12R, G12S, G12V, G13C, and G13D. 4. The method of claim 1, wherein the administration route is selected from the group consisting of parenteral and anal.

Details for Patent 9,526,709

Glossary

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Applicant	Tradename	Biologic Ingredient	Dosage Form	BLA	Approval Date	Patent No.	Expiredate
Eli Lilly And Company	ERBITUX	cetuximab	Injection	125084	02/12/2004	⤷ Try a Trial	2031-04-06
Eli Lilly And Company	ERBITUX	cetuximab	Injection	125084	03/28/2007	⤷ Try a Trial	2031-04-06
>Applicant	>Tradename	>Biologic Ingredient	>Dosage Form	>BLA	>Approval Date	>Patent No.	>Expiredate

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