Claims for Patent: 8,901,378

Summary for Patent: 8,901,378

Title:	Corn event TC1507 and methods for detection thereof
Abstract:	The invention provides DNA compositions that relate to transgenic insect resistant maize plants. Also provided are assays for detecting the presence of the maize TC1507 event based on the DNA sequence of the recombinant construct inserted into the maize genome and the DNA sequences flanking the insertion site. Kits and conditions useful in conducting the assays are provided.
Inventor(s):	Barbour; Eric (Johnston, IA), Bing; James Wayne (Ankeny, IA), Cardineau; Guy A. (Tempe, AZ), Cressman, Jr.; Robert F. (Wilmington, DE), Gupta; Manju (Carmel, IN), Locke; Mary E. Hartnett (Mickleton, NJ), Hondred; David (Ankeny, IA), Keaschall; Joseph W. (Clive, IA), Koziel; Michael G. (Raleigh, NC), Meyer; Terry EuClaire (Urbandale, IA), Moellenbeck; Daniel (Granger, IA), Narva; Kenneth Edwin (Carlsbad, CA), Nirunsuksiri; Wilas (Auburn, WA), Ritchie; Stephen W. (Omaha, NE), Rudert; Marjorie L. (Boone, IA), Sanders; Craig D. (Bear, DE), Shao; Aihua (Johnston, IA), Stelman; Steven Jeffrey (San Diego, CA), Stucker; David S. (Johnston, IA), Tagliani; Laura Ann (Zionsville, IN), Van Zante; William M. (Urbandale, IA)
Assignee:	Pioneer Hi-Bred International, Inc. (Johnston, IA)
Application Number:	12/914,271
Patent Claims:	1. A corn plant comprising a DNA construct, said DNA construct comprising a first and a second expression cassette, wherein said first expression cassette in operable linkage comprises (a) a maize ubiquitin promoter; (b) a 5' untranslated exon of a maize ubiquitin gene; (c) a maize ubiquitin intron; (d) a Cry1F encoding DNA molecule; and (e) a 3' ORF25 transcriptional terminator; and said second expression cassette comprising in operable linkage (i) a CaMV 35S promoter; (ii) a pat encoding DNA molecule; and (iii) a 3' transcriptional terminator from (CaMV) 35S comprising the nucleic acid sequence of positions 5843 to 6032 of SEQ ID NO: 25; and wherein the first and second expression cassettes are flanked by SEQ ID NO: 26 at the 5' end and SEQ ID NO: 27 at the 3' end. 2. The corn plant of claim 1, wherein the corn plant is a seed. 3. A method of producing an insect resistant corn plant comprising: (a) breeding with an insect resistant corn plant comprising in its genome DNA the DNA construct of claim 1 and (b) selecting a progeny of (a) by analyzing the genome of the progeny for the presence of the DNA construct of claim 1. 4. The method of claim 3, wherein breeding comprises crossing the insect resistant corn plant of (a) with a second plant. 5. The method of claim 3, wherein the insect resistant corn plant of (a) is the pollen parent for the crossing. 6. The method of claim 4, wherein the second plant is the pollen parent for the crossing. 7. The method of claim 3, wherein the progeny comprises the insect resistance of the insect resistant corn plant of (a). 8. The corn plant of claim 1, wherein the DNA construct comprises the polynucleotide of SEQ ID NO: 24.

Details for Patent 8,901,378

Applicant	Tradename	Biologic Ingredient	Dosage Form	BLA	Approval Date	Patent No.	Expiredate
Merck Sharp & Dohme Corp.	INTRON A	interferon alfa-2b	For Injection	103132	06/04/1986		2023-05-02
Merck Sharp & Dohme Corp.	INTRON A	interferon alfa-2b	For Injection	103132			2023-05-02
Merck Sharp & Dohme Corp.	INTRON A	interferon alfa-2b	Injection	103132			2023-05-02