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Last Updated: April 23, 2024

Claims for Patent: 8,822,646

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Summary for Patent: 8,822,646

Title:	Cancer therapies and pharmaceutical compositions used therein
Abstract:	The invention relates to compositions and methods to inhibit gene expression. In particular, the invention provides co-therapies comprising oligonucleotides plus other therapies to treat cancer.
Inventor(s):	Goodwin; Neal Clifford (Plainwell, MI), McGovren; James Patrick (Kalamazoo, MI)
Assignee:	ProNAi Therapeutics, Inc. (Kalamazoo, MI)
Application Number:	13/428,885
Patent Claims:	1. A pharmaceutical composition comprising: an oligonucleotide and an immunotherapeutic agent, wherein the oligonucleotide comprises an oligomer consisting of SEQ ID NOs:1250 or 1251 and the immunotherapeutic agent is rituximab. 2. The composition of claim 1, wherein the oligonucleotide comprises SEQ ID NO:1251. 3. The composition of claim 2, further comprising an additional oligonucleotide. 4. The composition of claim 3, wherein the additional oligonucleotide consists of SEQ ID NO:1250. 5. The composition of claim 1 wherein the oligonucleotide has a phosphorothiolate backbone.

Details for Patent 8,822,646

Glossary

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Applicant	Tradename	Biologic Ingredient	Dosage Form	BLA	Approval Date	Patent No.	Expiredate
Genentech, Inc.	RITUXAN	rituximab	Injection	103705	11/26/1997	⤷ Try a Trial	2025-12-01
Idec Pharmaceuticals Corp.	RITUXAN	rituximab	Injection	103737	02/19/2002	⤷ Try a Trial	2025-12-01
Genentech, Inc.	RITUXAN HYCELA	rituximab and hyaluronidase human	Injection	761064	06/22/2017	⤷ Try a Trial	2025-12-01
>Applicant	>Tradename	>Biologic Ingredient	>Dosage Form	>BLA	>Approval Date	>Patent No.	>Expiredate

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