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Last Updated: April 24, 2024

Claims for Patent: 8,821,873

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Summary for Patent: 8,821,873

Title:	Treatment of diffuse large-cell lymphoma with anti-CD20 antibody
Abstract:	The present invention concerns methods for the treatment of diffuse large cell lymphoma by administration of an anti-CD20 antibody and chemotherapy. Particular embodiments include the administration of anti-CD20 antibody in combination with chemotherapy comprising CHOP (cyclophosphamide, hydroxydaunorubicin/doxorubicin, vincristine, and prednisone/prednisolone) and/or in combination with a transplantation regimen.
Inventor(s):	White; Christine A. (Rancho Santa Fe, CA), Grillo-Lopez; Antonio J. (Rancho Santa Fe, CA)
Assignee:	Biogen Idec Inc. (Weston, MA)
Application Number:	14/045,375
Patent Litigation and PTAB cases:	See patent lawsuits and PTAB cases for patent 8,821,873
Patent Claims:	1. A method of treating a patient with diffuse large cell lymphoma comprising administering anti-CD20 antibody and chemotherapy to the patient, wherein the patient is >60 years old, wherein the chemotherapy comprises CHOP (cyclophosphamide, hydroxydaunorubicin/doxorubicin, vincristine, and prednisone/prednisolone), and wherein the anti-CD20 antibody is administered to the patient in combination with stem cell transplantation regimen. 2. The method of claim 1, wherein the antibody comprises a chimeric anti-CD20 antibody. 3. The method of claim 2, wherein the antibody comprises rituximab. 4. The method of claim 1, wherein the lymphoma is accompanied by bone marrow involvement. 5. A method of treating a patient with diffuse large cell lymphoma comprising administering rituximab and CHOP (cyclophosphamide, hydroxydaunorubicin/doxorubicin, vincristine, and prednisone/prednisolone) to the patient, in combination with stem cell transplantation, wherein the patient is >60 years old.

Details for Patent 8,821,873

Glossary

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Applicant	Tradename	Biologic Ingredient	Dosage Form	BLA	Approval Date	Patent No.	Expiredate
Genentech, Inc.	RITUXAN	rituximab	Injection	103705	11/26/1997	⤷ Try a Trial	2019-08-11
Idec Pharmaceuticals Corp.	RITUXAN	rituximab	Injection	103737	02/19/2002	⤷ Try a Trial	2019-08-11
Genentech, Inc.	RITUXAN HYCELA	rituximab and hyaluronidase human	Injection	761064	06/22/2017	⤷ Try a Trial	2019-08-11
>Applicant	>Tradename	>Biologic Ingredient	>Dosage Form	>BLA	>Approval Date	>Patent No.	>Expiredate

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