Claims for Patent: 8,765,683
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Summary for Patent: 8,765,683
Title: | T-140 peptide analogs having CXCR4 super-agonist activity for cancer therapy |
Abstract: | The present invention is directed to novel therapeutic uses of T-140 analog peptides and compositions comprising same. Specifically, the invention provides compositions and methods useful in cancer therapy. |
Inventor(s): | Peled; Amnon (Tel-Aviv, IL), Begin; Michal (Jerusalem, IL), Beider; Katia (Jerusalem, IL), Abraham; Michal (Mevasseret Zion, IL) |
Assignee: | Biokine Therapeutics Ltd. (Nes Ziona, IL) |
Application Number: | 13/360,751 |
Patent Claims: | 1. A method for treating lymphoma in a subject, comprising administering to the subject a therapeutically effective amount of an anti-CD20 antibody and a peptide
having an amino acid sequence as set forth in SEQ ID NO:1, thereby treating the lymphoma.
2. The method of claim 1, wherein said anti-CD20 antibody comprises rituximab. 3. A method for inducing lymphoma cell death in a subject in need thereof, comprising administering to the subject a therapeutically effective amount of an anti-CD20 antibody and a peptide having an amino acid sequence as set forth in SEQ ID NO:1, thereby inducing lymphoma cell death. 4. The method of claim 3, wherein said anti-CD20 antibody comprises rituximab. 5. A method for increasing the sensitivity of lymphoma cells to an anti-CD20 antibody, comprising administering to a subject in need thereof a sensitizing-effective amount of a peptide having an amino acid sequence as set forth in SEQ ID NO:1 in concurrent or sequential combination with the anti-CD20 antibody, thereby increasing the sensitivity of lymphoma cells to the anti-CD20 antibody. 6. The method of claim 5, wherein said anti-CD20 antibody comprises rituximab. |
Details for Patent 8,765,683
Applicant | Tradename | Biologic Ingredient | Dosage Form | BLA | Approval Date | Patent No. | Expiredate |
---|---|---|---|---|---|---|---|
Genentech, Inc. | RITUXAN | rituximab | Injection | 103705 | 11/26/1997 | ⤷ Try a Trial | 2026-12-21 |
Idec Pharmaceuticals Corp. | RITUXAN | rituximab | Injection | 103737 | 02/19/2002 | ⤷ Try a Trial | 2026-12-21 |
Genentech, Inc. | RITUXAN HYCELA | rituximab and hyaluronidase human | Injection | 761064 | 06/22/2017 | ⤷ Try a Trial | 2026-12-21 |
>Applicant | >Tradename | >Biologic Ingredient | >Dosage Form | >BLA | >Approval Date | >Patent No. | >Expiredate |
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