Claims for Patent: 8,637,655

Summary for Patent: 8,637,655

Title:	Amelogenin SNP on chromosome X
Abstract:	Disclosed are methods for gender determination in the intron 1 region of the amelogenin locus and a newly discovered single nucleotide polymorphism (SNP) within the X chromosome of the amelogenin locus which can cause allelic dropout. Also disclosed are kits useful in gender determination.
Inventor(s):	Mulero; Julio (Sunnyvale, CA), Green; Robert (Cupertino, CA), Lagace; Robert (Oakland, CA), Hennessy; Lori (San Mateo, CA)
Assignee:	Life Technologies Corporation (Carlsbad, CA)
Application Number:	12/856,530
Patent Claims:	1. A kit comprising a first primer and a second primer, wherein the first primer and the second primer form a PCR primer pair, wherein an amplicon generated by the PCR primer pair includes intron 1 of the amelogenin gene, and wherein the 3' terminal nucleotide of the first primer is complementary to the thymidine at position 83 of SEQ ID NO:1 wherein at least one of the primers is labeled. 2. The kit according to claim 1, wherein the first primer is SEQ ID NO:7. 3. The kit of claim 1, further comprising a third primer, wherein the 3' terminal nucleotide of the third primer is complementary to the cytosine at position 83 of SEQ ID NO:2. 4. The kit of claim 3, wherein the third primer is SEQ ID NO:6. 5. The kit of claim 1, wherein the label is a fluorescent label.

Details for Patent 8,637,655

Applicant	Tradename	Biologic Ingredient	Dosage Form	BLA	Approval Date	Patent No.	Expiredate
Merck Sharp & Dohme Corp.	INTRON A	interferon alfa-2b	For Injection	103132	06/04/1986		2039-02-26
Merck Sharp & Dohme Corp.	INTRON A	interferon alfa-2b	For Injection	103132			2039-02-26
Merck Sharp & Dohme Corp.	INTRON A	interferon alfa-2b	Injection	103132			2039-02-26