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Last Updated: March 29, 2024

Claims for Patent: 8,518,644


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Summary for Patent: 8,518,644
Title:Method of judging inflammatory disease by using single nucleotide polymorphism
Abstract: An object of the present invention is to identify a novel single nucleotide polymorphism (SNP) associated with the onset and the advancement of inflammatory diseases such as myocardial infarction. The present invention provides a method for judging an inflammatory disease which comprises detecting at least 1 type of genetic polymorphism existing in at least one gene selected from the group consisting of the LBP-32 gene, the TSBP gene, and the WAP gene.
Inventor(s): Tanaka; Toshihiro (Tokyo, JP), Nakamura; Yusuke (Kanagawa, JP), Ohnishi; Yozo (Tokyo, JP), Ozaki; Koichi (Tokyo, JP), Iida; Aritoshi (Kanagawa, JP), Hori; Masatsugu (Osaka, JP)
Assignee: Riken (Saitama, JP)
Application Number:11/813,450
Patent Claims:1. A method for detecting genetic polymorphisms existing in the LBP-32 gene, the TSBP gene, and the WAP12 gene which comprises: obtaining a biological sample containing an LBP-32 gene sequence, a TSBP gene sequence, and a 3' flanking region of a WAP12 gene sequence from a subject; and assaying for the presence of a group of single nucleotide polymorphisms consisting of an A or G at position 151 in intron 1 of the LBP-32 gene; an A or G at position 306 of exon 25 of the TSBP gene; and an A or G at nucleotide 1264 in the 3' flanking region of the WAP12 gene.

Details for Patent 8,518,644

Applicant Tradename Biologic Ingredient Dosage Form BLA Approval Date Patent No. Expiredate
Merck Sharp & Dohme Corp. INTRON A interferon alfa-2b For Injection 103132 06/04/1986 ⤷  Try a Trial 2025-01-07
Merck Sharp & Dohme Corp. INTRON A interferon alfa-2b For Injection 103132 ⤷  Try a Trial 2025-01-07
Merck Sharp & Dohme Corp. INTRON A interferon alfa-2b Injection 103132 ⤷  Try a Trial 2025-01-07
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Approval Date >Patent No. >Expiredate

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