You’re using a public version of DrugPatentWatch with 5 free searches available | Register to unlock more free searches. CREATE FREE ACCOUNT

Last Updated: March 28, 2024

Claims for Patent: 8,506,962


✉ Email this page to a colleague

« Back to Dashboard


Summary for Patent: 8,506,962
Title:Sustained release drug delivery systems comprising a water soluble therapeutic agent and a release modifier
Abstract: A biocompatible, sustained release intraocular drug delivery system comprising a protein or polynucleotide therapeutic agent, a polymeric carrier for the therapeutic agent and a long chain fatty alcohol release modifier. The biocompatible, sustained release intraocular drug delivery system can be used to treat an ocular condition.
Inventor(s): Trogden; John T. (Villa Park, CA), Lyons; Robert T. (Laguna Hills, CA)
Assignee: Allergan, Inc. (Irvine, CA)
Application Number:13/649,339
Patent Claims:1. A method for treating an ocular condition associated with neovascularization of the eye in a patient, the method comprising administering an extruded biodegradable intraocular implant to the patient by intravitreal injection, wherein the extruded biodegradable intraocular implant consists of: a) about 70-85% by weight of a biodegradable polymeric carrier, wherein the biodegradable polymeric carrier is a poly-lactide-co-glycolide (PLGA); b) about 10-20% by weight of an anti-VEGF antibody; and c) about 5-10% by weight of a saturated straight chain alcohol 16 to 26 carbon atoms in length.

2. The method of claim 1, wherein the anti-VEGF antibody is bevacizumab.

3. The method of claim 1, wherein the ocular condition is choroidal neovascularization.

4. The method of claim 1, wherein the implant is administered to the patient via a needle.

5. The method of claim 1, wherein said saturated straight chain alcohol is 1-eicosanol.

Make Better Decisions: Try a trial or see plans & pricing

Drugs may be covered by multiple patents or regulatory protections. All trademarks and applicant names are the property of their respective owners or licensors. Although great care is taken in the proper and correct provision of this service, thinkBiotech LLC does not accept any responsibility for possible consequences of errors or omissions in the provided data. The data presented herein is for information purposes only. There is no warranty that the data contained herein is error free. thinkBiotech performs no independent verification of facts as provided by public sources nor are attempts made to provide legal or investing advice. Any reliance on data provided herein is done solely at the discretion of the user. Users of this service are advised to seek professional advice and independent confirmation before considering acting on any of the provided information. thinkBiotech LLC reserves the right to amend, extend or withdraw any part or all of the offered service without notice.