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Last Updated: April 20, 2024

Claims for Patent: 8,486,898

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Summary for Patent: 8,486,898

Title:	Compounds and method for inhibiting the activity of gelatinase and collagenase
Abstract:	Compounds extracted from Rhodiola rosea have ability to inhibit gelatinases and collagenases activity. The compounds have the chemical structure as shown below. ##STR00001##
Inventor(s):	Lee; Ching-Kuo (Xindian, TW), Hsu; Chieh-Chih (Taichung, TW), Hsiao; George (Taipei, TW), Juang; Shin-Hun (Taichung, TW)
Assignee:	Taipei Medical University (TMU) (Taipei, TW) China Medical University (Taichung, TW)
Application Number:	13/167,060
Patent Claims:	1. A purified compound 4GX having a chemical formula as follow: ##STR00007## 2. A method of inhibiting the activity of MMP-2, Pro MMP-2, Pro-MMP-9, collagenase type IV or any combinations thereof containing, the method comprises: applying a composition containing an effective amount of a compound 4GX having a formula shown below on skin ##STR00008##

Details for Patent 8,486,898

Glossary

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Applicant	Tradename	Biologic Ingredient	Dosage Form	BLA	Approval Date	Patent No.	Expiredate
Smith & Nephew, Inc.	SANTYL	collagenase	Ointment	101995	06/04/1965	⤷ Try a Trial	2030-07-20
>Applicant	>Tradename	>Biologic Ingredient	>Dosage Form	>BLA	>Approval Date	>Patent No.	>Expiredate

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