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Last Updated: March 29, 2024

Claims for Patent: 8,444,988


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Summary for Patent: 8,444,988
Title:Cancer treatment method
Abstract: A method of treating cancer is described including administration of a 4-quinazolineamine and at least one other anti-neoplastic agent as well as a pharmaceutical combination including the 4-quinazolineamines.
Inventor(s): Lackey; Karen Elizabeth (Durham, NC), Mullin; Robert J. (Durham, NC), Spector; Neil (Chapel Hill, NC), Wood, III; Edgar Raymond (Durham, NC), Xia; Wenle (Durham, NC)
Assignee: GlaxoSmithKline LLC (Philadelphia, PA)
Application Number:13/294,496
Patent Claims:1. A method of treating breast cancer in a mammal, comprising administering to said mammal a therapeutically effective amount of: (a) the compound of formula II: ##STR00009## or a pharmaceutically acceptable salt thereof; and (b) trastuzumab.

2. The method of claim 1, wherein the mammal is human.

3. The method of claim 1, wherein the pharmaceutically acceptable salt is ditosylate.

4. A method of treating breast cancer in a mammal, comprising administering to said mammal a therapeutically effective amount of: (a) ##STR00010## ditosylate monohydrate; and (b) trastuzumab.

Details for Patent 8,444,988

Applicant Tradename Biologic Ingredient Dosage Form BLA Approval Date Patent No. Expiredate
Genentech, Inc. HERCEPTIN trastuzumab For Injection 103792 09/25/1998 ⤷  Try a Trial 2021-01-16
Genentech, Inc. HERCEPTIN trastuzumab For Injection 103792 02/10/2017 ⤷  Try a Trial 2021-01-16
Genentech, Inc. HERCEPTIN HYLECTA trastuzumab and hyaluronidase-oysk Injection 761106 02/28/2019 ⤷  Try a Trial 2021-01-16
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Approval Date >Patent No. >Expiredate

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