Claims for Patent: 8,444,988
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Summary for Patent: 8,444,988
Title: | Cancer treatment method |
Abstract: | A method of treating cancer is described including administration of a 4-quinazolineamine and at least one other anti-neoplastic agent as well as a pharmaceutical combination including the 4-quinazolineamines. |
Inventor(s): | Lackey; Karen Elizabeth (Durham, NC), Mullin; Robert J. (Durham, NC), Spector; Neil (Chapel Hill, NC), Wood, III; Edgar Raymond (Durham, NC), Xia; Wenle (Durham, NC) |
Assignee: | GlaxoSmithKline LLC (Philadelphia, PA) |
Application Number: | 13/294,496 |
Patent Claims: | 1. A method of treating breast cancer in a mammal, comprising administering to said mammal a therapeutically effective amount of: (a) the compound of formula II: ##STR00009## or a
pharmaceutically acceptable salt thereof; and (b) trastuzumab.
2. The method of claim 1, wherein the mammal is human. 3. The method of claim 1, wherein the pharmaceutically acceptable salt is ditosylate. 4. A method of treating breast cancer in a mammal, comprising administering to said mammal a therapeutically effective amount of: (a) ##STR00010## ditosylate monohydrate; and (b) trastuzumab. |
Details for Patent 8,444,988
Applicant | Tradename | Biologic Ingredient | Dosage Form | BLA | Approval Date | Patent No. | Expiredate |
---|---|---|---|---|---|---|---|
Genentech, Inc. | HERCEPTIN | trastuzumab | For Injection | 103792 | 09/25/1998 | ⤷ Try a Trial | 2021-01-16 |
Genentech, Inc. | HERCEPTIN | trastuzumab | For Injection | 103792 | 02/10/2017 | ⤷ Try a Trial | 2021-01-16 |
Genentech, Inc. | HERCEPTIN HYLECTA | trastuzumab and hyaluronidase-oysk | Injection | 761106 | 02/28/2019 | ⤷ Try a Trial | 2021-01-16 |
>Applicant | >Tradename | >Biologic Ingredient | >Dosage Form | >BLA | >Approval Date | >Patent No. | >Expiredate |
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