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Last Updated: April 24, 2024

Claims for Patent: 8,242,079

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Summary for Patent: 8,242,079

Title:	Lactoferrin in the treatment of malignant neoplasms and other hyperproliferative diseases
Abstract:	The present invention relates to methods of treating a hyperproliferative disease by administering a composition of lactoferrin alone or in combination with standard anti-cancer therapies.
Inventor(s):	Varadhachary; Atul (Houston, TX), Barsky; Rick (Houston, TX), Pericle; Federica (Houston, TX), Petrak; Karel (Houston, TX), Wang; Yenyun (Houston, TX)
Assignee:	Agennix Incorporated (Houston, TX)
Application Number:	12/964,327
Patent Claims:	1. A method of treating non small cell lung and renal cancer in a mammalian subject in need thereof comprising administering chemotherapy, biotherapy, immunotherapy, surgery, radiotherapy, or a combination thereof to the subject in combination with orally administering to the subject a therapeutically effective amount of full-length mature human lactoferrin composition. 2. The method of claim 1, wherein the lactoferrin composition is administered in combination with chemotherapy, radiotherapy, or both. 3. The method of claim 1, wherein the chemotherapy comprises paclitaxel, docetaxel, doxorubicin, daunorubicin, adriamycin, mitomycin, actinomycin D, bleomycin, plicomycin, vincristine, vinblastine, cisplatin, etoposide, Tumor Necrosis Factor, carmustine, melphalan, cyclophosphamide, chlorambucil, busulfan, docetaxel, lomustine, carboplatin, procarbazine, mechlorethamine, irinotecan, topotecan, ifosfamide, nitrosurea, tamoxifen, raloxifene, toremifene, idoxifene, droloxifene, TAT-59, zindoxifene, trioxifene, ICI 182,780, EM-800, gemcitabinen, navelbine, transplatinum, 5-Fluorouracil, methotrexate, temazolomide, mylotarg, dolastatin-10, or bryostatin. 4. The method of claim 1, wherein the chemotherapy comprises a platinum-based chemotherapy. 5. The method of claim 4, wherein the platinum-based chemotherapy comprises cisplatin or carboplatin. 6. The method of claim 1, wherein the chemotherapy comprises a taxane-based chemotherapy. 7. The method of claim 6, wherein the taxane-based chemotherapy comprises docetaxel. 8. The method of claim 1, wherein the chemotherapy comprises paclitaxel. 9. The method of claim 1, wherein the lactoferrin composition is administered in combination with radiotherapy. 10. The method of claim 1, wherein the lactoferrin composition is administered in combination with biotherapy. 11. The method of claim 1, wherein the lactoferrin composition is administered in combination with immunotherapy. 12. The method of claim 1, wherein the lactoferrin composition is administered in combination with surgery.

Details for Patent 8,242,079

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Applicant	Tradename	Biologic Ingredient	Dosage Form	BLA	Approval Date	Patent No.	Expiredate
Wyeth Pharmaceuticals Llc	MYLOTARG	gemtuzumab ozogamicin	For Injection	761060	09/01/2017	⤷ Try a Trial	2022-05-10
>Applicant	>Tradename	>Biologic Ingredient	>Dosage Form	>BLA	>Approval Date	>Patent No.	>Expiredate

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