Claims for Patent: 8,147,752

Summary for Patent: 8,147,752

Title:	Sterilants and sterilization method for aseptic filling
Abstract:	The present invention provides an aqueous solution of a sterilant of peracetic acid series for use in aseptic filling comprised predominantly of hydrogen peroxide, peracetic acid and water wherein a pH of the aqueous solution is 2.about.4, a ratio of the concentration of hydrogen peroxide/the concentration of peracetic acid is 0.7 or less, and the concentration of peracetic acid is 500.about.3000 ppm as well as a sterilization method wherein the sterilant thereof is used. The sterilant of peracetic acid series exhibits an excellent sterilizing effect even at an extremely low concentration of peracetic acid and so is economically advantageous. What is more, washing of the sterilant with sterile water after sterilization of a container is attained by injecting sterile water even for a short period of time to such level that the sterilized container can be filled with foods and drinks, so that the sterilant is remarkable in economical value and working efficiency. The sterilization method is carried out by heating the sterilant of peracetic acid series and/or a container for foods and the like or the interior surface thereof at 60.degree. C. or higher to obtain more effective sterilizing effect and can be used in a recycling system, so far as a ratio of the concentration of hydrogen peroxide/the concentration of peracetic acid be maintained.
Inventor(s):	Iwashita; Takeshi (Kanagawa, JP), Sunohara; Chikako (Kanagawa, JP), Kominami; Kenichi (Kanagawa, JP)
Assignee:	Toyo Seikan Kaisha, Ltd. (Tokyo, JP)
Application Number:	12/304,838
Patent Claims:	1. A disinfecting method for a sterile packing system, comprising: providing a peracetic acid based disinfectant wherein a peracetic acid based disinfectant aqueous solution containing as principal components thereof hydrogen peroxide, peracetic acid, and water has a pH of from 2 to 4, a hydrogen peroxide concentration/peracetic acid concentration ratio of 0.7 or lower, and a peracetic acid concentration of from 500 ppm to 3000 ppm; bringing said disinfectant aqueous solution and/or a disinfectant application inner surface being subjected to sterile packing to a temperature of from 60.degree. C. to 95.degree. C.; spraying said peracetic acid based disinfectant aqueous solution, in a condition in which air is mixed therewith, onto at least said application inner surface; and subsequently cleaning off said peracetic acid based disinfectant aqueous solution with sterile water. 2. The disinfecting method for a sterile packing system according to claim 1, wherein the application inner surface subjected to sterile packing is at least one surface selected from the group consisting of food and beverage product containers, medical product containers, caps and lids for said containers, equipment installed in sterile packing spaces, and interior wall surfaces forming boundaries for said sterile packing. 3. The disinfecting method of claim 1, wherein the peracetic acid concentration is 3000 ppm.

Details for Patent 8,147,752

Applicant	Tradename	Biologic Ingredient	Dosage Form	BLA	Approval Date	Patent No.	Expiredate
Merck Sharp & Dohme Corp.	ZOSTAVAX	zoster vaccine live	For Injection	125123	05/25/2006		2039-09-22