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Last Updated: March 28, 2024

Claims for Patent: 8,039,602


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Summary for Patent: 8,039,602
Title:Isolated genomic polynucleotide fragments from the p15 region of chromosome 11
Abstract: The invention is directed to isolated genomic polynucleotide fragments from the p15 arm of chromosome 11.
Inventor(s): Ryan; James W. (Augusta, GA)
Assignee: Ryogen LLC (Suffern, NY)
Application Number:09/999,121
Patent Claims:1. An isolated genomic polynucleotide, said polynucleotide obtainable from the p15 region of human chromosome 11 selected from the group consisting of: (a) the polynucleotide of SEQ ID NO:11; (b) a polynucleotide fragment of (a) that comprises nucleotides 10471-29787 of SEQ ID NO:11 and (c) the full complement of (a) or (b).

2. A nucleic acid construct comprising the polynucleotide of claim 1.

3. An expression vector comprising the polynucleotide of claim 1.

4. A recombinant host cell comprising the polynucleotide of claim 1.

5. A method for obtaining human cluster of differentiation antigen 81 comprising: (a) culturing the recombinant host cell of claim 4 under conditions that provide for the expression of obtaining human cluster of differentiation antigen 81 and (b) recovering said human cluster of differentiation antigen 81.

6. An isolated polynucleotide consisting of an intron fragment of SEQ ID NO:11 or its complementary sequence, wherein said intron fragment or its complementary sequence is at least 20 nucleotides in length.

7. A composition comprising the polynucleotide of claim 1 and a carrier or diluent.

8. A composition comprising the polynucleotide of claim 6 and a carrier or diluent.

9. A kit comprising the polynucleotide of claim 1.

10. A kit comprising the polynucleotide of claim 6.

11. The isolated polynucleotide of claim 6, wherein said intron is selected from the group consisting of nucleotides 10537-23332, 23447-27014, 27114-27892, 27965-28333, 28442-28789, 28892-29548 and 29636-29724 of SEQ ID NO:11 or reverse strand thereof.

12. The polynucleotide according to claim 1, wherein said polynucleotide encodes a polypeptide depicted in SEQ ID NO:5.

13. An isolated polynucleotide consisting of 50-2000 contiguous nucleotides in sequence segments of an intron region of SEQ ID NO:11, or its complementary sequence.

14. An isolated polynucleotide consisting of an intron region of SEQ ID NO:11, or its complementary sequence.

15. A kit comprising the isolated polynucleotide of claim 13.

16. A composition comprising the isolated polynucleotide of claim 13.

17. A composition comprising the isolated polynucleotide of claim 14.

18. A kit comprising the isolated polynucleotide of claim 14.

Details for Patent 8,039,602

Applicant Tradename Biologic Ingredient Dosage Form BLA Approval Date Patent No. Expiredate
Merck Sharp & Dohme Corp. INTRON A interferon alfa-2b For Injection 103132 06/04/1986 ⤷  Try a Trial 2020-10-31
Merck Sharp & Dohme Corp. INTRON A interferon alfa-2b For Injection 103132 ⤷  Try a Trial 2020-10-31
Merck Sharp & Dohme Corp. INTRON A interferon alfa-2b Injection 103132 ⤷  Try a Trial 2020-10-31
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Approval Date >Patent No. >Expiredate

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