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Last Updated: April 25, 2024

Claims for Patent: 7,908,087

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Summary for Patent: 7,908,087

Title:	Methods of identifying latent splice sites
Abstract:	A method of identifying latent splice sites, the method comprising identifying at least one intronic in-frame stop codon located upstream of a 5\' splice site sequence being a latent splice site, thereby identifying latent splice sites.
Inventor(s):	Sperling; Joseph (Jerusalem, IL), Sperling; Ruth (Jerusalem, IL)
Assignee:	Yeda Research And Development Co. Ltd. (Rehovot, IL) Yissum Research Development Company of the Hebrew University of Jerusalem (Jerusalem, IL)
Application Number:	10/505,884
Patent Claims:	1. A computer program product, comprising at least one non-transitory computer readable medium having a computer readable program code embodied therein, said computer readable program code adapted to be executed to implement a method of identifying a gene having a latent splice site, the method comprising: identifying an in-frame stop codon in an intron sequence of the gene, and in said intron sequence, identifying a 5' splice site downstream of said in-frame stop codon, said 5' splice site being a latent splice site capable of transcribing an RNA to thereby identify the gene having the latent splice site; and providing data on said gene having the latent splice site in a user readable format. 2. The method of claim 1, wherein said identifying a latent splice site is effected on a large scale. 3. A method of identifying a gene having a latent splice site, the method comprising: identifying, using a computing processor, an in-frame stop codon in an intron sequence of the gene, and in said intron sequence, identifying, using said computing processor, a 5' splice site downstream of said in-frame stop codon, said 5' splice site being a latent splice site capable of transcribing an RNA to thereby identify the gene having the latent splice site; and providing data on said gene having the latent splice site in a user readable format.

Details for Patent 7,908,087

Glossary

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Applicant	Tradename	Biologic Ingredient	Dosage Form	BLA	Approval Date	Patent No.	Expiredate
Merck Sharp & Dohme Corp.	INTRON A	interferon alfa-2b	For Injection	103132	06/04/1986	⤷ Try a Trial	2039-02-26
Merck Sharp & Dohme Corp.	INTRON A	interferon alfa-2b	For Injection	103132		⤷ Try a Trial	2039-02-26
Merck Sharp & Dohme Corp.	INTRON A	interferon alfa-2b	Injection	103132		⤷ Try a Trial	2039-02-26
>Applicant	>Tradename	>Biologic Ingredient	>Dosage Form	>BLA	>Approval Date	>Patent No.	>Expiredate

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