Claims for Patent: 7,771,414

Summary for Patent: 7,771,414

Title:	Controlled release devices for therapeutic treatments of spinal discs
Abstract:	A device includes a first reservoir configured to include a degrading agent, a first valve in fluid communication with the first reservoir, and a reservoir driver configured to manipulate the first reservoir to effect a first reservoir condition based on a first tissue condition. The first valve is configured to open in response to the first reservoir condition associated with the first reservoir.
Inventor(s):	Trieu; Hai H. (Cordova, TN)
Assignee:	Warsaw Orthopedic, Inc. (N/A)
Application Number:	11/410,221
Patent Claims:	1. A device comprising: a first reservoir; a second reservoir; a first valve in fluid communication with the first reservoir, the first valve configured to open based on a first tissue condition of pressure or hydration; a second valve in fluid communication with the second reservoir, the second valve configured to open based on a second tissue condition and wherein the second valve is configured to close based on the first tissue condition; and a first osmotic driver coupled to the first reservoir, wherein the first osmotic driver is configured to adjust a pressure of the first reservoir based on a condition of a tissue of pressure or hydration. 2. The device of claim 1, wherein the first valve is configured to close based on the second tissue condition. 3. The device of claim 1, wherein the first reservoir is configured to include a first agent, wherein the first agent is a first stimulating agent. 4. The device of claim 3, wherein the second reservoir is configured to include a second agent, and wherein the second agent is a second stimulating agent. 5. The device of claim 4, wherein the first stimulating agent is a regenerating agent. 6. The device of claim 4, wherein the second stimulating agent is a therapeutic agent. 7. The device of claim 3, wherein the second reservoir is configured to include a second agent, and wherein the second agent is a degrading agent. 8. The device of claim 7, wherein the degrading agent is selected from the group consisting of chymopapain, collagenase, chondroitinase, keratanase, human proteolytic enzymes, papaya protenase, or any combination thereof. 9. The device of claim 1, wherein the first tissue condition is associated with a low average pressure in a tissue. 10. The device of claim 1, wherein the second tissue condition is associated with a high average pressure in a tissue. 11. The device of claim 1, wherein the first osmotic driver is coupled to the second reservoir. 12. The device of claim 1, further comprising a second osmotic driver coupled to the second reservoir. 13. The device of claim 12, wherein the first and second osmotic drivers have a different response to a condition of a tissue.

Details for Patent 7,771,414

Applicant	Tradename	Biologic Ingredient	Dosage Form	BLA	Approval Date	Patent No.	Expiredate
Discure Medical, Llc	CHYMODIACTIN	chymopapain	For Injection	018663	11/10/1982		2039-03-29
Discure Medical, Llc	CHYMODIACTIN	chymopapain	For Injection	018663	08/21/1984		2039-03-29
Smith & Nephew, Inc.	SANTYL	collagenase	Ointment	101995	06/04/1965		2039-03-29