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Last Updated: March 29, 2024

Claims for Patent: 7,702,104


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Summary for Patent: 7,702,104
Title:System and method for securing genomic information
Abstract: A system and method for securing an electronic transmission of a nucleotide chain. A security system is provided that comprises: a system for identifying coding and non-coding regions in the nucleotide chain; and a system for selectively encrypting only the coding regions identified in the nucleotide chain.
Inventor(s): Batra; Virinder Mohan (Chapel Hill, NC), Altunay; Mine (Raleigh, NC), Warade; Chetna Dnyandeo (Arlington, MA), Colonnese; Daniel (Durham, NC), Wilber; Lindsay Kathleen (Charlottesville, VA), Vadlamudi; Satyaprasad (Chapel Hill, NC)
Assignee: International Business Machines Corporation (Armonk, NY)
Application Number:10/816,393
Patent Claims:1. A computer-implemented security system for securing an electronic version of a nucleotide chain sequence, wherein the nucleotide chain sequence comprises at least a portion of a genome of an organism, the system comprising: a computer hardware apparatus; and a computer program that, when loaded and executed, controls the computer hardware apparatus such that it carries out: on a first application, identifying a sequence of at least one exon and a sequence of at least one intron in the nucleotide chain sequence; selectively encrypting the sequence of only the at least one exon identified in the nucleotide chain to provide security over a network, wherein the selectively encrypting only the sequence of the at least one exon utilizes cipher block chain encrypting; outputting the electronic version of the nucleotide chain sequence, including both the encrypted sequence of the at least one exon and the unencrypted sequence of the at least one intron, wherein the outputting includes transmitting the encrypted sequence of the at least one exon and the unencrypted sequence of the at least one intron; and on a second application, receiving the encrypted sequence of the at least one exon and the unencrypted sequence of the at least one intron; decrypting the encrypted sequence of the at least one exon; and regenerating the nucleotide chain from the decrypted sequence of the at least one exon and the unencrypted sequence of the at least one intron to re-form the original nucleotide chain sequence.

2. The computer-implemented security system of claim 1, wherein the transmitting includes packaging the encrypted sequence of the at least one exon and the unencrypted sequence of the at least one intron into at least one XML document.

3. The computer-implemented security system of claim 1, wherein the transmitting of the encrypted sequence of the at least one exon and the sequence of the at least one unencrypted intron utilizes web services.

4. The computer-implemented security system of claim 1, wherein the receiving comprises receiving the encrypted sequence of the at least one exon and the unencrypted sequence of the at least one intron into a bioinformatics database for receiving nucleotide chain queries.

5. A computer implemented method for transmitting a nucleotide chain sequence, wherein the nucleotide chain sequence comprises at least a portion of a genome of an organism, the method comprising: on a computer hardware apparatus, identifying a sequence of at least one exon and a sequence of at least one intron in the nucleotide chain sequence; selectively encrypting the sequence of only the at least one exon identified in the nucleotide chain, wherein the selectively encrypting only the sequence of the at least one exon utilizes cipher block chain encrypting; transmitting the encrypted sequence of the at least one exon and the unencrypted sequence of the at least one intron; receiving the encrypted sequence of the at least one exon and the unencrypted sequence of the at least one intron; decrypting the encrypted sequence of the at least one exon; regenerating the nucleotide chain sequence from the decrypted sequence of the at least one exon and unencrypted sequence of the at least one intron to re-form the original nucleotide chain sequence; and outputting the regenerated nucleotide chain sequence.

6. The method of claim 5, comprising the further step of querying a bioinformatics database with the received nucleotide chain sequence.

7. The method of claim 5, wherein the encrypted sequence of the at least one exon and the unencrypted sequence of the at least one intron are transmitted in at least one XML document.

8. The method of claim 5, wherein the encrypted sequence of the at least one exon and the unencrypted sequence of the at least one intron are transmitted using web services.

9. A program product stored on a recordable storage medium comprising instructions executable by a computer system that when executed, cause the computer system to implement a method encoding a nucleotide chain sequence, wherein the nucleotide chain sequence comprises at least a portion of a genome of an organism, the method comprising: identifying a sequence of at least one exon and a sequence of at least one intron in the nucleotide chain sequence; selectively encrypting only the sequence of the at least one exon identified in the nucleotide chain sequence to provide security over a network, wherein the selectively encrypting includes utilizing cipher block chain encrypting; and outputting the nucleotide chain sequence including both the encrypted sequence of the at least one exon and the unencrypted sequence of the at least one intron over the network, the outputting including transmitting the encrypted sequence of the at least one exon and the unencrypted sequence of the at least one intron; receiving the encrypted sequence of the at least one exon and the unencrypted sequence of the at least one intron; decrypting the encrypted sequence of the at least one exon; and regenerating the nucleotide chain from the decrypted sequence of the at least one exon and the unencrypted sequence of the at least one intron to re-form the original nucleotide chain sequence.

10. The program product of claim 9, wherein the encrypted sequence of the at least one exon and unencrypted sequence of the at least one intron are stored in at least one XML document.

11. A program product stored on a recordable storage medium comprising instructions executable by a computer system that when executed, cause the computer system to implement a method for decrypting an encrypted nucleotide chain, wherein the nucleotide chain sequence comprises at least a portion of a genome of an organism, the method comprising: identifying an encrypted sequence of at least one exon and an unencrypted sequence of at least one intron in the nucleotide chain sequence; selectively decrypting only the encrypted sequence of the at least one exon identified in the nucleotide chain sequence, wherein the sequence of the at least one exon is encrypted using cipher block chain encryption; reassembling the sequence of the at least one exon and the sequence of the at least one intron to generate a decrypted nucleotide chain sequence; and outputting the decrypted nucleotide chain sequence.

12. The program product of claim 11, wherein the sequence of the at least one exon and the sequence of the at least one intron are stored in at least one XML document.

13. The program product of claim 11, further comprising querying a bioinformatics database with the decrypted nucleotide chain sequence.

14. The computer-implemented security system of claim 2, wherein the packaging occurs prior to selectively encrypting the sequence of only the at least one exon identified in the nucleotide chain.

15. The computer-implemented security system of claim 2, wherein the packaging includes packaging the sequence of the at least one exon in a first unique XML document and packaging the sequence of the at least one intron in a second unique XML document.

16. The method of claim 7, wherein the encrypted sequence of the at least one exon and the unencrypted sequence of the at least one intron are packaged into the at least one XML document prior to selectively encrypting the sequence of only the at least one exon identified in the nucleotide chain.

Details for Patent 7,702,104

Applicant Tradename Biologic Ingredient Dosage Form BLA Approval Date Patent No. Expiredate
Merck Sharp & Dohme Corp. INTRON A interferon alfa-2b For Injection 103132 06/04/1986 ⤷  Try a Trial 2039-02-26
Merck Sharp & Dohme Corp. INTRON A interferon alfa-2b For Injection 103132 ⤷  Try a Trial 2039-02-26
Merck Sharp & Dohme Corp. INTRON A interferon alfa-2b Injection 103132 ⤷  Try a Trial 2039-02-26
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Approval Date >Patent No. >Expiredate

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