You’re using a public version of DrugPatentWatch with 5 free searches available | Register to unlock more free searches. CREATE FREE ACCOUNT

Last Updated: April 20, 2024

Claims for Patent: 7,666,675

✉ Email this page to a colleague

« Back to Dashboard

Summary for Patent: 7,666,675

Title:	Nestin-expressing hair follicle stem cells
Abstract:	Hair follicle stem cells are isolated from mammals by isolating nestin-expressing cells. These hair follicle stem cells are a source of adult stem cells for autologous or heterologous stem cell therapy. The stem cells can be systemically implanted into the mammal or directly implanted into the organ. In addition, the stem cells may be further differentiated in vitro and then implanted systemically or directly into the mammal.
Inventor(s):	Li; Lingna (San Diego, CA), Yang; Meng (San Diego, CA)
Assignee:	AntiCancer, Inc. (San Diego, CA)
Application Number:	10/251,657
Patent Claims:	1. A method to isolate mouse hair follicle stem cells, which method comprises providing individual hair follicles from transgenic mice whose genome comprises a nucleotide sequence encoding a fluorescent protein under the control of nestin control sequences, and isolating cells producing the fluorescent protein from the bulge area of the hair follicle immediately below the sebaceous gland during the telogen phase or early anagen phase. 2. The method of claim 1 that further comprises culturing said isolated hair follicle stem cells in media to produce differentiated cells, which are neurons, astrocytes, or smooth muscle cells wherein the culture medium comprises fetal bovine serum (FBS), brain derived neurotrophic factor (BDNF), platelet derived growth factor (PDGF) or ciliary neurotrophic factor (CNTF). 3. Neurons, astrocytes, or smooth muscle cells obtained by the method of claim 2. 4. The method of claim 1 wherein the transgenic mice carry a nucleotide sequence encoding a fluorescent protein under the control of the nestin second-intron enhancer. 5. Hair follicle stem cells isolated by the method of claim 1.

Details for Patent 7,666,675

Glossary

Subscribe to access the full database, or Try a Trial
Applicant	Tradename	Biologic Ingredient	Dosage Form	BLA	Approval Date	Patent No.	Expiredate
Merck Sharp & Dohme Corp.	INTRON A	interferon alfa-2b	For Injection	103132	06/04/1986	⤷ Try a Trial	2021-09-20
Merck Sharp & Dohme Corp.	INTRON A	interferon alfa-2b	For Injection	103132		⤷ Try a Trial	2021-09-20
Merck Sharp & Dohme Corp.	INTRON A	interferon alfa-2b	Injection	103132		⤷ Try a Trial	2021-09-20
>Applicant	>Tradename	>Biologic Ingredient	>Dosage Form	>BLA	>Approval Date	>Patent No.	>Expiredate

Make Better Decisions: Try a trial or see plans & pricing

Drugs may be covered by multiple patents or regulatory protections. All trademarks and applicant names are the property of their respective owners or licensors. Although great care is taken in the proper and correct provision of this service, thinkBiotech LLC does not accept any responsibility for possible consequences of errors or omissions in the provided data. The data presented herein is for information purposes only. There is no warranty that the data contained herein is error free. thinkBiotech performs no independent verification of facts as provided by public sources nor are attempts made to provide legal or investing advice. Any reliance on data provided herein is done solely at the discretion of the user. Users of this service are advised to seek professional advice and independent confirmation before considering acting on any of the provided information. thinkBiotech LLC reserves the right to amend, extend or withdraw any part or all of the offered service without notice.