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Last Updated: April 18, 2024

Claims for Patent: 7,541,148

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Summary for Patent: 7,541,148

Title:	Method for detecting base mutation
Abstract:	The present invention relates to methods for precisely and effectively detecting mutations of organism.
Inventor(s):	Kim; Nam-Keun (Gyeonggi-do, KR), Kim; Suk-Joon (Seoul, KR), Kim; Soo-Ok (Seoul, KR), Kim; Eun-Ok (Seoul, KR), Moon; Myung-Soon (Seoul, KR), Yoo; Wang-Don (Gyeonggi-do, KR), Lee; Chang-Hong (Seoul, KR), Chung; Hyun-Jae (Gyeonggi-do, KR), Jee; Mi-Sun (Seoul, KR), Hwang; Seong-Gyu (Seoul, KR), Hong; Sun-Pyo (Seoul, KR)
Assignee:	Genematrix, Inc. (Seoul, KR)
Application Number:	11/726,725
Patent Claims:	1. A primer for analyzing a gene mutation comprising a primer binding sequence 1, a restriction enzyme recognition sequence and a primer binding sequence 2, wherein two or more single stranded polynucleotide fragments that contain at least one mutation sequence respectively and have sizes of 2-32 bases are produced by amplifying with the primer and cleaving with two or more restriction enzymes recognizing the restriction enzyme recognition sequence, and the primer is selected from the group consisting of SEQ ID NO: 2, 7, 12, 20, 25 and 30. 2. The primer according to claim 1, wherein the restriction enzymes have different optimum temperatures. 3. The primer according to claim 2, wherein a first restriction enzyme is Fok1 and a second restriction enzyme is BstF5. 4. The primer according to claim 1, wherein the primer is used for mutation analysis of the 2741.sup.ST or 3597.sup.TH base site of the 4.sup.TH intron of human maspin gene or for mutation analysis of lamivudine resistant hepatitis B virus or hepatitis C virus.

Details for Patent 7,541,148

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Applicant	Tradename	Biologic Ingredient	Dosage Form	BLA	Approval Date	Patent No.	Expiredate
Merck Sharp & Dohme Corp.	INTRON A	interferon alfa-2b	For Injection	103132	06/04/1986	⤷ Try a Trial	2022-10-18
Merck Sharp & Dohme Corp.	INTRON A	interferon alfa-2b	For Injection	103132		⤷ Try a Trial	2022-10-18
Merck Sharp & Dohme Corp.	INTRON A	interferon alfa-2b	Injection	103132		⤷ Try a Trial	2022-10-18
>Applicant	>Tradename	>Biologic Ingredient	>Dosage Form	>BLA	>Approval Date	>Patent No.	>Expiredate

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