Claims for Patent: 7,531,173
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Summary for Patent: 7,531,173
Title: | Ophthalmic composition of a VEGF antagonist |
Abstract: | Methods of reducing or treating angiogenesis and/or inflammation associated with eye injury in a subject in need thereof, comprising administering an agent capable of blocking or inhibiting vascular endothelial growth factor (VEGF) are provided. The methods are useful for inhibiting or ameliorating eye injury, particularly acute or subacute corneal injury and feature local administration (for example, subconjunctival injection or eye drops). |
Inventor(s): | Wiegand; Stanley J. (Croton-on-Hudson, NY), Cao; Jingtai (Chappaqua, NY) |
Assignee: | Regeneron Pharmaceuticals, Inc. (Tarrytown, NY) |
Application Number: | 11/998,746 |
Patent Claims: | 1. An ophthalmic composition comprising a vascular endothelial growth factor (VEGF) antagonist in a pharmaceutically acceptable carrier, wherein the VEGF antagonist is
VEGFR1R2-Fc.DELTA.C1(a) polypeptide.
2. The ophthalmic composition of claim 1, which is a liquid, gel, ointment, salve, or sustained release formulation. |
Details for Patent 7,531,173
Applicant | Tradename | Biologic Ingredient | Dosage Form | BLA | Approval Date | Patent No. | Expiredate |
---|---|---|---|---|---|---|---|
Regeneron Pharmaceuticals, Inc. | EYLEA | aflibercept | Injection | 125387 | 11/18/2011 | ⤷ Try a Trial | 2039-03-29 |
Regeneron Pharmaceuticals, Inc. | EYLEA | aflibercept | Injection | 125387 | 08/16/2018 | ⤷ Try a Trial | 2039-03-29 |
>Applicant | >Tradename | >Biologic Ingredient | >Dosage Form | >BLA | >Approval Date | >Patent No. | >Expiredate |
International Patent Family for US Patent 7,531,173
Country | Patent Number | Estimated Expiration |
---|---|---|
World Intellectual Property Organization (WIPO) | 2006088650 | ⤷ Try a Trial |
United States of America | 7303748 | ⤷ Try a Trial |
United States of America | 2008085276 | ⤷ Try a Trial |
United States of America | 2006172944 | ⤷ Try a Trial |
European Patent Office | 1877438 | ⤷ Try a Trial |
Canada | 2621047 | ⤷ Try a Trial |
Australia | 2006214658 | ⤷ Try a Trial |
>Country | >Patent Number | >Estimated Expiration |
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