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Last Updated: March 29, 2024

Claims for Patent: 7,429,692


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Summary for Patent: 7,429,692
Title:Sucrose synthase 3 promoter from rice and uses thereof
Abstract: Rice sucrose synthase 3 regulatory regions suitable for directing expression of a heterologous nucleic acid are described, as well as nucleic acid constructs that include these regulatory regions. Also disclosed are transgenic plants that contain such constructs and methods of producing such transgenic plants.
Inventor(s): Dang; David Vandinh (Oak Park, CA)
Assignee: Ceres, Inc. (Thousand Oaks, CA)
Application Number:11/274,890
Patent Claims:1. An isolated nucleic acid comprising a regulatory region comprising the nucleotide sequence set forth in SEQ ID NO:1, wherein said regulatory region directs transcription, in a plant ovule within 24 hours post-fertilization, of an operably linked heterologous polynucleotide.

2. The nucleic acid of claim 1 wherein said regulatory region comprises an intron.

3. An isolated nucleic acid comprising a regulatory region comprising the nucleotide sequence set forth in SEQ ID NO:1, wherein said regulatory region directs transcription in an unfertilized plant ovule of an operably linked heterologous polynucleotide.

4. The nucleic acid of claim 3 wherein said regulatory region comprises an intron.

5. A nucleic acid construct comprising the nucleic acid of claim 1 operably linked to a heterologous polynucleotide.

6. The nucleic acid construct of claim 5 wherein said heterologous polynucleotide comprises a nucleic acid sequence encoding a polypeptide.

7. The nucleic acid construct of claim 5 wherein said heterologous polynucleotide is in an antisense orientation relative to said regulatory region.

8. The nucleic acid construct of claim 5 wherein said heterologous polynucleotide is transcribed into an antisense RNA capable of inhibiting expression of a DNA methyltransferase.

9. The nucleic acid construct of claim 5 wherein said heterologous polynucleotide is transcribed into an interfering RNA.

10. The nucleic acid construct of claim 5 wherein said heterologous polynucleotide is transcribed into an interfering RNA that inhibits transcription of a DNA methyltransferase.

11. A transgenic plant or plant cell wherein said plant or plant cell comprises the nucleic acid of claim 1 operably linked to a heterologous polynucleotide.

12. The transgenic plant or plant cell of claim 11 wherein said heterologous polynucleotide comprises a nucleic acid sequence encoding a polypeptide.

13. The transgenic plant or plant cell of claim 11 wherein said heterologous polynucleotide is in an antisense orientation relative to said regulatory region.

14. The transgenic plant or plant cell of claim 11 wherein said heterologous polynucleotide is transcribed into an interfering RNA.

15. A method of producing a transgenic plant, said method comprising (a) introducing into a plant cell an isolated polynucleotide comprising the nucleic acid of claim 1 operably linked to a heterologous polynucleotide, and (b) growing a plant from said plant cell.

16. The method of claim 15 wherein said heterologous polynucleotide comprises a nucleic acid sequence encoding a polypeptide.

17. The method of claim 15 wherein said heterologous polynucleotide is in an antisense orientation relative to said regulatory region.

18. The method of claim 15 wherein said heterologous polynucleotide is transcribed into an interfering RNA.

Details for Patent 7,429,692

Applicant Tradename Biologic Ingredient Dosage Form BLA Approval Date Patent No. Expiredate
Merck Sharp & Dohme Corp. INTRON A interferon alfa-2b For Injection 103132 06/04/1986 ⤷  Try a Trial 2024-10-14
Merck Sharp & Dohme Corp. INTRON A interferon alfa-2b For Injection 103132 ⤷  Try a Trial 2024-10-14
Merck Sharp & Dohme Corp. INTRON A interferon alfa-2b Injection 103132 ⤷  Try a Trial 2024-10-14
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Approval Date >Patent No. >Expiredate

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