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Last Updated: April 20, 2024

Claims for Patent: 7,351,414

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Summary for Patent: 7,351,414

Title:	Method of reducing the risk of bone fracture
Abstract:	The invention relates to a method for increasing the toughness and/or stiffness of bone and/or reducing the likelihood and/or severity of bone fracture by administering a parathyroid hormone. The method can be employed to increase toughness or stiffness of bone at a site of a potential or actual trauma, such as the hip or spine of a person at risk of or suffering from osteoporosis. The method of the invention can reduce the incidence of vertebral fracture, reduce the incidence of multiple vertebral fractures, reduce the severity of vertebral fractur and/or reduce the incidence of non-vertebral fracture.
Inventor(s):	Gaich; Gregory A. (Indianapolis, IN), Dere; Willard H. (Westlake Village Ventura, CA), Hock; Janet M. (Indianapolis, IN)
Assignee:	Eli Lilly and Company (Indianapolis, IN)
Application Number:	11/684,996
Patent Litigation and PTAB cases:	See patent lawsuits and PTAB cases for patent 7,351,414
Patent Claims:	1. A method for the treatment of a woman with osteoporosis and at risk for bone fracture comprising administering to said woman human parathyroid hormone (1-34) in a daily dose of 20 .mu.g, without concurrent administration of an antiresorptive agent other than vitamin D or calcium, said treatment reducing the risk of vertebral and nonvertebral bone fracture. 2. The method of claim 1, wherein the osteoporosis is selected from advanced-stage osteoporosis, spinal osteoporosis, and steroid-induced osteoporosis. 3. A method for the treatment of a man with osteoporosis and at risk for bone fracture comprising administering to said man human parathyroid hormone (1-34) in a daily dose of 20 .mu.g, without concurrent administration of an antiresorptive agent other than vitamin D or calcium, said treatment reducing the risk of vertebral and non-vertebral bone fracture. 4. The method of claim 3 in which said man has hypogonadal osteoporosis.

Details for Patent 7,351,414

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Applicant	Tradename	Biologic Ingredient	Dosage Form	BLA	Approval Date	Patent No.	Expiredate
Nps Pharmaceuticals, Inc.	NATPARA	parathyroid hormone	For Injection	125511	01/23/2015	⤷ Try a Trial	2018-08-19
>Applicant	>Tradename	>Biologic Ingredient	>Dosage Form	>BLA	>Approval Date	>Patent No.	>Expiredate

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