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Last Updated: March 29, 2024

Claims for Patent: 7,256,329


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Summary for Patent: 7,256,329
Title:Nucleic acid sequences and methods of use for the production of plants with modified polyunsaturated fatty acids
Abstract: By this invention, novel nucleic acid sequences are provided, wherein said nucleic acid sequence is a genomic sequence of a plant desaturase encoding sequence. Also provided in the present invention are the promoter and intron sequences of the desaturase genomic sequences. Furthermore, recombinant DNA constructs employing the polynucleotide sequences are provided. The instant invention also provides methods for the modification of fatty acid compositions in host plant cells.
Inventor(s): Fillatti; Joanne (Davis, CA)
Assignee: Calgene LLC (Davis, CA)
Application Number:10/606,772
Patent Claims:1. A soybean plant having a nucleic acid molecule comprising a promoter functional in a host plant cell operably linked to a polynucleotide that has at least 90% identity to SEQ ID NO: 2, a complement thereof, or a fragment of either, and a transcriptional termination region functional in said host plant cell, wherein a seed of said soybean plant exhibits a modified fatty acid composition that is about 26-80% oleic acid, about 2.97-49.92% linoleic acid, and about 3.38-8.81% linolenic acid.

2. The soybean plant according to claim 1, wherein said polynucleotide has at least 95% identity to SEQ ID NO: 2, a complement thereof, or a fragment of either.

3. The soybean plant according to claim 1, wherein said polynucleotide has at least 97% identity to SEQ ID NO: 2, a complement thereof, or a fragment of either.

4. The soybean plant according to claim 1, wherein said polynucleotide has at least 98% identity to SEQ ID NO: 2, a complement thereof, or a fragment of either.

5. The soybean plant according to claim 1, wherein said polynucleotide is SEQ ID NO: 2, a complement thereof, or a fragment of either.

6. The soybean plant according to claim 1, wherein said promoter is a heterologous promoter.

7. An soybean plant having a nucleic acid molecule comprising a promoter functional in a host plant cell operably linked to a polynucleotide that is a fad2 intron or complement thereof or fragment of either, wherein said polynucleotide has at least 90% identity to SEQ ID NO: 2, a complement thereof, or a fragment of either, and a transcriptional termination region functional in said host plant cell, wherein a seed of said soybean plant exhibits a modified fatty acid composition that is about 26-80% oleic acid, about 2.97-49.92% linoleic acid, and about 3.38-8.81% linolenic acid.

8. The soybean plant according to claim 7, wherein said polynucleotide is SEQ ID NO: 2, a complement thereof, or a fragment of either.

9. The soybean plant according to claim 7, wherein said promoter is a heterologous promoter.

10. A method of modifying the fatty acid composition in a seed of soybean plant comprising: growing an oilseed plant that has a nucleic acid molecule comprising a promoter functional in a host plant cell operably linked to a polynucleotide that is a fad2 intron or complement thereof or fragment of either, wherein said polynucleotide has at least 90% identity to SEQ ID NO: 2, a complement thereof, or a fragment of either, and a transcriptional termination region functional in said host plant cell, and harvesting said seed of said soybean plant, wherein said seed exhibits a modified fatty acid composition that is about 26-80% oleic acid, about 2.97-49.92% linoleic acid, and about 3.38-8.81% linolenic acid.

11. The soybean plant according to claim 10, wherein said polynucleotide has at least 95% identity to SEQ ID NO: 2, a complement thereof, or a fragment of either.

12. The soybean plant according to claim 10, wherein said polynucleotide has at least 97% identity to SEQ ID NO: 2, a complement thereof, or a fragment of either.

13. The soybean plant according to claim 10, wherein said polynucleotide has at least 98% identity to SEQ ID NO: 2, a complement thereof, or a fragment of either.

14. The soybean plant according to claim 10, wherein said polynucleotide is SEQ ID NO: 2, a complement thereof, or a fragment of either.

15. The soybean plant according to claim 10, wherein said promoter is a heterologous promoter.

16. The soybean plant according to claim 1, wherein said polynucleotide has at least 99% identity to SEQ ID NO: 2, a complement thereof, or fragment of either.

17. The soybean plant according to claim 7, wherein said polynucleotide has at least 95% identity to SEQ ID NO: 2, a complement thereof, or a fragment of either.

18. The soybean plant according to claim 7, wherein said polynucleotide has at least 97% identity to SEQ ID NO: 2, a complement thereof, or a fragment of either.

19. The soybean plant according to claim 7, wherein said polynucleotide has at least 98% identity to SEQ ID NO: 2, a complement thereof, or a fragment of either.

20. The soybean plant according to claim 7, wherein said polynucleotide has at least 99% identity to SEQ ID NO: 2, a complement thereof, or a fragment of either.

21. The soybean plant according to claim 10, wherein said polynucleotide has at least 99% identity to SEQ ID NO: 2, a complement thereof, or a fragment of either.

22. The soybean plant according to claim 1, wherein said polynucleotide is capable of suppressing fad2.

23. The soybean plant according to claim 7, wherein said polynucleotide is capable of suppressing fad2.

24. The soybean plant according to claim 10, wherein said polynucleotide is capable of suppressing fad2.

Details for Patent 7,256,329

Applicant Tradename Biologic Ingredient Dosage Form BLA Approval Date Patent No. Expiredate
Merck Sharp & Dohme Corp. INTRON A interferon alfa-2b For Injection 103132 06/04/1986 ⤷  Try a Trial 2019-08-26
Merck Sharp & Dohme Corp. INTRON A interferon alfa-2b For Injection 103132 ⤷  Try a Trial 2019-08-26
Merck Sharp & Dohme Corp. INTRON A interferon alfa-2b Injection 103132 ⤷  Try a Trial 2019-08-26
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Approval Date >Patent No. >Expiredate

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