You’re using a public version of DrugPatentWatch with 5 free searches available | Register to unlock more free searches. CREATE FREE ACCOUNT

Last Updated: April 25, 2024

Claims for Patent: 7,252,826

✉ Email this page to a colleague

« Back to Dashboard

Summary for Patent: 7,252,826

Title:	Modified mite allergen and pharmaceutical uses thereof
Abstract:	The present invention provides a modified Dermatophagoides pteronyssinus allergen Der p 5 protein which has ability to inhibit IgE binding when exposed against to the antigen. A method for treating allergy comprising administrating a therapeutically effective dose of the modified D. pteronyssinus allergen Der p 5 protein to a subject suffering from allergy Der p 5 is also provided.
Inventor(s):	Hsu; Ching-Hsiang (Tainan County, TW), Su; Wei-Chih (Tainan County, TW)
Assignee:	GenMont Biotech Inc. (TW)
Application Number:	10/654,020
Patent Claims:	1. A modified Dermatophagoides pteronyssinus allergen Der p 5 protein, wherein at least one of amino acid residues 44, 77, 99, and 103 of wild-type D. pteronyssinus allergen Der p 5 protein of SEQ ID NO.2 is substituted with alanine. 2. The modified D. pteronyssinus allergen Der p 5 protein according to claim 1, wherein the modified D. pteronyssinus allergen Der p 5 protein has the amino acid sequence selected from the group consisting of the sequences of SEQ ID NOs:4, 6 and 8. 3. A pharmaceutical composition comprising a therapeutically effective dose of the modified D. pteronyssinus allergen Der p 5 protein according to claim 1 and a pharmaceutically acceptable carrier. 4. A pharmaceutical composition comprising a therapeutically effective dose of the modified D. pteronyssinus allergen Der p 5 protein according to claim 2 and a pharmaceutically acceptable carrier. 5. The modified D. pteronyssinus allergen Der p 5 protein according to claim 1, wherein amino acid residue 44 of wild-type D. pteronyssinus allergen Der p 5 protein of SEQ ID NO: 2 is substituted with alanine. 6. The modified D. pteronyssinus allergen Der p 5 protein according to claim 1, wherein amino acid residue 77 of wild-type D. pteronyssinus allergen Der p 5 protein of SEQ ID NO: 2 is substituted with alanine. 7. The modified D. pteronyssinus allergen Der p 5 protein according to claim 1, wherein amino acid residue 99 of wild-type D. pteronyssinus allergen Der p 5 protein of SEQ ID NO: 2 is substituted with alanine. 8. The modified D. pteronyssinus allergen Der p 5 protein according to claim 1, wherein amino acid residue 103 of wild-type D. pteronyssinus allergen Der p 5 protein of SEQ ID NO: 2 is substituted with alanine.

Details for Patent 7,252,826

Glossary

Subscribe to access the full database, or Try a Trial
Applicant	Tradename	Biologic Ingredient	Dosage Form	BLA	Approval Date	Patent No.	Expiredate
Greer Laboratories, Inc.	N/A	insects (whole body), mite dermatophagoides pteronyssinus	Injection	101835	09/15/1958	⤷ Try a Trial	2022-11-07
>Applicant	>Tradename	>Biologic Ingredient	>Dosage Form	>BLA	>Approval Date	>Patent No.	>Expiredate

Make Better Decisions: Try a trial or see plans & pricing

Drugs may be covered by multiple patents or regulatory protections. All trademarks and applicant names are the property of their respective owners or licensors. Although great care is taken in the proper and correct provision of this service, thinkBiotech LLC does not accept any responsibility for possible consequences of errors or omissions in the provided data. The data presented herein is for information purposes only. There is no warranty that the data contained herein is error free. thinkBiotech performs no independent verification of facts as provided by public sources nor are attempts made to provide legal or investing advice. Any reliance on data provided herein is done solely at the discretion of the user. Users of this service are advised to seek professional advice and independent confirmation before considering acting on any of the provided information. thinkBiotech LLC reserves the right to amend, extend or withdraw any part or all of the offered service without notice.