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Last Updated: March 28, 2024

Claims for Patent: 6,814,724


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Summary for Patent: 6,814,724
Title: Water purification pack
Abstract:An apparatus and methods are disclosed for purifying fluid, such as potable water, to quality levels suitable for medical application, particularly to applications involving injection of the fluid into a human body. The apparatus comprises a portable purification pack constructed for a single use. The pack houses depth filtration, activated carbon, mixed bed ion exchange resins and terminal filtration stages in series. The terminal filter comprises a fine (microfiltration or ultrafiltration), permeable membrane, treated with an endotoxin-binding chemistry. In contrast with semi-permeable osmotic membranes, the permeable membrane produces high flow rates at relatively low pressures, while still safely purifying fluid to injection quality.
Inventor(s): Taylor; Michael A. (Napa, CA)
Assignee: PrisMedical Corporation (Napa, CA)
Application Number:10/339,702
Patent Claims:1. A method of producing injectable quality of water, comprising: providing a portable purification pack comprising a housing surrounding a plurality of purification elements in series; providing non-sterile water to an inlet of the housing under a feed pressure of less than about 20 psi; passing the water through the plurality of purification elements; and outputting purified water from an outlet of the housing, wherein the purified water has an organic content, conductivity, pH level and particulate contamination level suitable for injection into the human body.

2. The method of claim 1, further comprising injecting the purified water into a human body.

3. The method of claim 2, further comprising dissolving reagents within the purified water prior to injecting the purified water into the human being.

4. The method of claim 3, wherein dissolving reagents in the purified water comprises passing the purified water from the outlet into a drug reagent cartridge housing dry formulations suitable for forming a medical treatment solution.

5. The method of claim 4, wherein the medical solution comprises peritoneal dialysate.

6. The method of claim 1, wherein outputting the purified water has a flux rate of greater than about 30 mL/min.

7. The method of claim 6, wherein outputting the purified water has a flux rate of greater than about 100 mL/min.

8. The method of claim 7, wherein the feed pressure is between about 5 psi and 10 psi.

9. The method of claim 1, wherein the plurality of purification elements comprises a terminal filter having a porosity of no more than about 0.5 .mu.m.

10. The method of claim 1, wherein the purified water has a total organic content of less than about 500 ppb; conductivity of less than about 2.0 .mu. Siemens; pH between about 4.5 and 7.5; fewer than about 12 particles/mL of particles greater than 10 .mu.m; fewer than about 2 particles/mL of particles greater than 25 .mu.m; and lower than about 0.025 ng/mL of endotoxins.

11. A method for producing fluid for medical application, comprising: providing a portable housing; passing non-sterile fluid through the housing; retaining particulate contamination, organic matter, dissociated ions, and endotoxins from the feed fluid within purification elements in the housing; and outputting fluid suitable for medical applications from the housing.

12. The method of claim 11, wherein the purification elements include a mixed bed of anion-exchange and cation-exchange resins.

13. The method of claim 12, wherein the purification elements further comprise a depth filtration stage and an organic adsorption stage.

14. The method of claim 11, wherein retaining endotoxins comprises passing the feed fluid through a permeable membrane treated with a quaternary amine exchange chemistry.

15. The method of claim 14, wherein retaining endotoxins comprises passing the feed fluid through a permeable ultrafiltration membrane having a nominal cut-off porosity of between about 10,000 and 30,000 molecular weight.

16. The method of claim 11, wherein retaining particulate contamination comprises passing the feed fluid through a depth filtration stage.

17. The method of claim 11, wherein the housing contains an outlet including an irreversible lock.

18. method for producing fluid for medical application, comprising: providing a portable housing; passing non-sterile fluid through the housing; retaining particulate contamination, organic matter, dissociated ions, and endotoxins from the feed fluid within purification elements in the housing, the purification elements arranged in series; and outputting fluid suitable for medical applications from the housing.

19. The method of claim 18, wherein the purification elements include a mixed bed of anion-exchange and cation-exchange resins.

20. The method of claim 19, wherein the purification elements further comprise a depth filtration stage and an organic adsorption stage.

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