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Last Updated: April 18, 2024

Claims for Patent: 6,290,993

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Summary for Patent: 6,290,993

Title:	Compositions containing mimosa phenolic compounds
Abstract:	The invention relates to topical cosmetic and pharmaceutical composition for enhancing collagen levels in skin cells, the compositions comprising an effective amount of a biologically active phenolic compound-containing extract, or active fraction thereof, obtainable from Mimosa pudica.
Inventor(s):	Anderson; Jon (Hauppauge, NY), Declercq; Lieve (Ekeren, BE), Collins; Donald F. (Plainview, NY), Mammone; Thomas (Farmingdale, NY), Declerq; Lieve (Ekeren, BE), Corstjens; Hugo A. L. (Maaseik, BE)
Assignee:	E-L Management Corp. (New York, NY)
Application Number:	09/360,884
Patent Claims:	1. A method for treating or or reducing the appearance of fine lines and wrinkles on the skin comprising applying to the skin of a person in need thereof a composition comprising an effective amount of a biologically active phenolic compound-containing Mimosa pudica plant extract, or active fraction thereof. 2. The method of claim 1 in which the phenolic is a flavonoid or flavone aglycone. 3. The method of claim 1 in which the phenolic is a C-glycosyl flavonoid or an aglycone thereof. 4. The method of claim 1 in which the phenolic is maysin, ax-4"-OHmaysin, 2"-O-rhamnosylorientin, and 2"-O-rhamnosyl isoorientin, luteolin, or a combination thereof. 5. The method of claim 1 in which the composition comprises about 0.001 to about 10% of phenolic compound-containing extract or active fraction thereof. 6. A method of inhibiting collagenase activity in the skin comprising applying to the skin of a person in need thereof a composition comprising an effective amount of a biologically active phenolic compound-containing Mimosa pudica plant extract, or active fraction thereof. 7. The method of claim 6, in which the phenolic is a flavonoid or flavone aglycone. 8. The method of claim 6 in which the phenolic is a C-glycosyl flavonoid or an aglycone thereof. 9. The method of claim 6 in which the phenolic is maysin, ax-4"-OHmaysin, 2"-O-rhamnosylorientin, and 2"-O-rhamnosyl isoorientin, luteolin, or a combination thereof. 10. The method of claim 6 in which the composition comprises about 0.001 to about 10% of phenolic compound-containing extract or active fraction thereof. 11. A method of increasing skin firmness comprising applying to the skin of a person in need thereof a composition an effective amount of a biologically active phenolic compound-containing Mimosa pudica plant extract, or active fraction thereof. 12. The method of claim 11 comprising applying to the skin in which the phenolic is a flavonoid or flavone aglycone. 13. The method of claim 11 in which the phenolic is a C-glycosyl flavonoid or an aglycone thereof. 14. The method of claim 11 in which the phenolic is maysin, ax-4"-OH-maysin, 2"-O-rhamnosylorientin, and 2"-O-rhamnosyl isoorientin, luteolin, or a combination thereof. 15. A method of claim 11 in which the composition comprises about 0.001 to about 10% of phenolic compound-containing extract or active fraction thereof.

Details for Patent 6,290,993

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Applicant	Tradename	Biologic Ingredient	Dosage Form	BLA	Approval Date	Patent No.	Expiredate
Smith & Nephew, Inc.	SANTYL	collagenase	Ointment	101995	06/04/1965	⤷ Try a Trial	2039-02-26
>Applicant	>Tradename	>Biologic Ingredient	>Dosage Form	>BLA	>Approval Date	>Patent No.	>Expiredate

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