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Last Updated: April 24, 2024

Claims for Patent: 5,786,211

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Summary for Patent: 5,786,211

Title:	Adeno-associated virus materials and methods
Abstract:	The present invention provides adeno-associated virus (AAV) materials and methods which are useful for DNA delivery to cells. More particularly, the invention provides recombinant AAV (rAAV) genomes, methods for packaging rAAV genomes, stable host cell lines producing rAAV and methods for delivering genes of interest to cells utilizing the rAAV. Particularly disclosed are rAAV useful in generating immunity to human immunodeficiency virus-1 and in therapeutic gene delivery for treatment of neurological disorders.
Inventor(s):	Johnson; Philip R. (Gahanna, OH)
Assignee:	Children\'s Hospital, Inc. (Columbus, OH)
Application Number:	08/475,391
Patent Claims:	1. A composition comprising infectious recombinant adeno-associated virus comprising a recombinant adeno-associated virus genome, wherein said recombinant adeno-associated virus genome comprises the cytomegalovirus (CMV) early promoter, the rabbit .beta.-globin intron, the human immunodeficiency virus rev/env sequences and the rabbit .beta.-globin polyadenylation signal.

Details for Patent 5,786,211

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Applicant	Tradename	Biologic Ingredient	Dosage Form	BLA	Approval Date	Patent No.	Expiredate
Merck Sharp & Dohme Corp.	INTRON A	interferon alfa-2b	For Injection	103132	06/04/1986	⤷ Try a Trial	2015-07-28
Merck Sharp & Dohme Corp.	INTRON A	interferon alfa-2b	For Injection	103132		⤷ Try a Trial	2015-07-28
Merck Sharp & Dohme Corp.	INTRON A	interferon alfa-2b	Injection	103132		⤷ Try a Trial	2015-07-28
>Applicant	>Tradename	>Biologic Ingredient	>Dosage Form	>BLA	>Approval Date	>Patent No.	>Expiredate

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