DrugPatentWatch Database Preview➤ Get the DrugPatentWatch Daily Briefing
« Back to Dashboard
Summary for Patent: 5,714,349
|Title:||Synthetic gene coding for human parathyroid hormone|
|Abstract:||Disclosed are (1) a DNA containing a synthetic gene for expression of human parathyroid hormone represented by the following DNA sequence: TCTGTG TCCGAGATTC AGTTAATGCA TAACCTTGGC AAACATTTGA ACTCCATGGA GCGTGTAGAA TGGCTGCGTA AGAAGTTGCA GGATGTGCAC AATTTTGTTG CCTTAGGTGC CCCATTGGCT CCTCGTGATG CTGGTTCCCA AAGACCACGT AAAAAGGAAG ACAATGTCTT AGTTGAGAGC CATGAAAAAT CCCTAGGCGA GGCAGACAAG GCCGATGTGA ATGTATTAAC TAAAGCTAAA TCCCAG (2) a method for producing the DNA described in (1), which comprises enzymatically ligating a plurality of oligodeoxynucleotides to one another to form the DNA and inserting the DNA into a vector if necessary, (3) a transformant transformed by the DNA described in (1), and (4) a method for producing human parathyroid hormone which comprises cultivating the transformant described in (3), accumulating human parathyroid hormone in a culture medium, and collecting the same, whereby hPTH can be allowed to express in large amounts in a system using E. coli as a host.|
|Inventor(s):||Fukuda; Tsunehiko (Kyoto, JP), Oshika; Yuri (Osaka, JP), Yamada; Takao (Osaka, JP)|
|Assignee:||Takeda Chemical Industries, Ltd. (Osaka, JP)|
|Patent Claims:||1. Plasmid pE-PTH.
2. An Escherichia coil transformed with plasmid pE-PTH.
3. A method for producing human parathyroid hormone which comprises cultivating an Escherichia coli transformed with plasmid pE-PTH under conditions suitable for expression of said human parathyroid hormone and recovering the same.
Summary for Patent: ⤷ Free Forever Trial
|Applicant||Tradename||Biologic Ingredient||Dosage Form||BLA||Number||Approval Date||Patent No.||Assignee||Estimated Patent Expiration||Status||Orphan||Source|
|Nps Pharms Inc||NATPARA||parathyroid hormone||INJECTABLE;INJECTION||125511||001||2015-01-23||⤷ Free Forever Trial||Takeda Chemical Industries, Ltd. (Osaka, JP)||2010-09-28||RX||Orphan||search|
|Nps Pharms Inc||NATPARA||parathyroid hormone||INJECTABLE;INJECTION||125511||002||2015-01-23||⤷ Free Forever Trial||Takeda Chemical Industries, Ltd. (Osaka, JP)||2010-09-28||RX||Orphan||search|
|Nps Pharms Inc||NATPARA||parathyroid hormone||INJECTABLE;INJECTION||125511||003||2015-01-23||⤷ Free Forever Trial||Takeda Chemical Industries, Ltd. (Osaka, JP)||2010-09-28||RX||Orphan||search|
|Nps Pharms Inc||NATPARA||parathyroid hormone||INJECTABLE;INJECTION||125511||004||2015-01-23||⤷ Free Forever Trial||Takeda Chemical Industries, Ltd. (Osaka, JP)||2010-09-28||RX||Orphan||search|
|>Applicant||>Tradename||>Biologic Ingredient||>Dosage Form||>BLA||>Number||>Approval Date||>Patent No.||>Assignee||>Estimated Patent Expiration||>Status||>Orphan||>Source|
|Country||Patent Number||Estimated Expiration|
|Austria||125299||⤷ Free Forever Trial|
|Canada||2052396||⤷ Free Forever Trial|
|Germany||69111371||⤷ Free Forever Trial|
|European Patent Office||0483509||⤷ Free Forever Trial|
|Japan||3252916||⤷ Free Forever Trial|
|Japan||H0541989||⤷ Free Forever Trial|
|>Country||>Patent Number||>Estimated Expiration|
Make Better Decisions: Try a trial or see plans & pricing
Serving leading biopharmaceutical companies globally:
Drugs may be covered by multiple patents or regulatory protections. All trademarks and applicant names are the property of their respective owners or licensors. Although great care is taken in the proper and correct provision of this service, thinkBiotech LLC does not accept any responsibility for possible consequences of errors or omissions in the provided data. The data presented herein is for information purposes only. There is no warranty that the data contained herein is error free. thinkBiotech performs no independent verification of facts as provided by public sources nor are attempts made to provide legal or investing advice. Any reliance on data provided herein is done solely at the discretion of the user. Users of this service are advised to seek professional advice and independent confirmation before considering acting on any of the provided information. thinkBiotech LLC reserves the right to amend, extend or withdraw any part or all of the offered service without notice.