Claims for Patent: 5,687,714

Summary for Patent: 5,687,714

Title:	Self-cleaning endotracheal tube apparatus
Abstract:	An endotracheal tube apparatus (10) which can efficiently impart air to the lungs of a human or animal while preventing the harmful build up of mucus deposits on critical parts of the apparatus. This endotracheal tube apparatus features an endotracheal tube (12) and a catheter (14) which are together inserted into the trachea (16) of a human or animal to a point slightly above the carina (28) of the lungs. Humidified air entrained with water or saline droplets from reservoir (56) is pumped into and through the catheter. The catheter features a reverse thrust catheter (RTC) tip (60, 62, 64, 80) at its distal end (24) which reverses the direction of humidified air flow away from the lungs. The RTC tip serves to protect the lungs from accumulation of water or saline droplets while the water or saline droplets continually clean both the catheter and endotracheal tube by dissolving and expelling any mucus which might otherwise accumulate.
Inventor(s):	Kolobow; Theodor (Rockville, MD), Trawoger; Rudolf (Bethesda, MD)
Assignee:	The United States of America as represented by the Department of Health (Washington, DC)
Application Number:	08/541,846
Patent Claims:	1. An apparatus for intratracheal ventilation of human or animal lungs comprising: an endotracheal tube for insertion into a human or animal trachea to a point above a human's or animal's lungs; a catheter positioned within said endotracheal tube, having proximal and distal ends; a source of humidified air flow connected to the proximal end of said catheter to provide humidified air flow through said catheter; means to entrain liquid droplets to said humidified air flow so that the air flow in said catheter consists of humidified air with entrained liquid droplets, said liquid droplets being entrained in an amount sufficient to detectably dissolve mucus deposits on said catheter and within said endotracheal tube while not producing a significant accumulation of water in a human's or animal's lungs; and, a flow-reversing catheter tip affixed to the distal end of said catheter having an exit port directed away from a human's or animal's lungs. 2. The intratracheal ventilation apparatus of claim 1 wherein approximately 1 drop of water is entrained every minute. 3. The intratracheal ventilation apparatus of claim 1 wherein said catheter and flow-reversing catheter tip are formed as an integral part of said endotracheal tube. 4. The intratracheal ventilation apparatus of claim 1 wherein said source of humidified air includes: a compressed oxygen tank; a compressed air tank; a flow meter connected to said oxygen and air tanks to mix oxygen and air in desired proportions; and, a humidifier connected to said flowmeter to humidify the mixture of oxygen and air received from the flow meter. 5. The intratracheal ventilation apparatus of claim 1 wherein said liquid droplets are sterile water. 6. The intratracheal ventilation apparatus of claim 1 wherein said liquid droplets are saline solution. 7. An apparatus for intratracheal ventilation of human or animal lungs comprising: an endotracheal tube for insertion into a human or animal trachea to a point above a human's or animal's lungs; a catheter positioned within said endotracheal tube, having proximal and distal ends; a source of humidified air flow connected to the proximal end of said catheter to provide humidified air flow through said catheter; means to entrain liquid droplets to said humidified air flow so that the air flow in said catheter consists of humidified air with entrained liquid droplets, said means to entrain including: a reservoir of sterile water; a pump for pumping water from said reservoir; and, a connector piece operably connected to said pump and said catheter for pumping water droplets into the humidified air passing through said catheter; and, a flow-reversing catheter tip affixed to the distal end of said catheter having an exit port directed away from a human's or animal's lungs. 8. A method for self-cleaning intratracheal ventilation of a human or animal comprising the steps of: selecting an endotracheal tube, with proximal and distal ends, which can comfortably be inserted into a human's or animal's trachea; selecting a catheter, with proximal and distal ends, to fit within said endotracheal tube; affixing a flow-reversing tip onto the distal end of said catheter which is capable of reversing the direction of air flow as the air exits said catheter; inserting both said endotracheal tube and said catheter into a human or animal's trachea until their distal ends reach a selected point above a human's or animal's lungs; attaching the proximal end of said catheter to source of humidified air into which liquid droplets are entrained, said liquid droplets being entrained in an amount sufficient to detectably dissolve mucus deposits on said catheter and within said endotracheal tube while not producing a significant accumulation of water in a human's or animal's lungs; and, infusing a mixture of humidified air and oxygen into a human's or animal's lungs through said catheter. 9. The method for self-cleaning intratracheal ventilation of claim 8 wherein said liquid droplets consist of sterilized water. 10. The method for self-cleaning intratracheal ventilation of claim 8 wherein said liquid droplets consist of saline. 11. The method for self-cleaning intratracheal ventilation of claim 9 wherein 1 drop of water is entrained for every 15 liters of air flow. 12. The method for self-cleaning intratracheal ventilation of claim 8 wherein the selected point above the lungs is 1 cm above the carina of the lungs. 13. The method for self-cleaning intratracheal ventilation of claim 8 further including the step of affixing detectable markers to the distal end of said endotracheal tube and said catheter to allow their insertion to a selected point above the lungs to be confirmed with x-rays.

Details for Patent 5,687,714

Applicant	Tradename	Biologic Ingredient	Dosage Form	BLA	Approval Date	Patent No.	Expiredate
Merck Sharp & Dohme Corp.	ZOSTAVAX	zoster vaccine live	For Injection	125123	05/25/2006		2039-09-23