Claims for Patent: 5,639,459

Summary for Patent: 5,639,459

Title:	Compositions for treatment of the hair
Abstract:	The invention provides a composition for the treatment for the hair, scalp and skin to improve condition and to assist in hair regrowth which comprises a pharmaceutically acceptable oxalate of a group Ia or Ia or ammonium oxalate metal disposed in a pharmaceutically acceptable carrier of diluent therefor. Preferably, the group IIa metal is calcium and the pharmaceutically acceptable carrier or diluent is an ointment.
Inventor(s):	Bouras; Elias (West Sussex, PO21 4XL, GB3)
Assignee:
Application Number:	08/464,746
Patent Claims:	1. A pharmaceutical composition for restoration of hair loss by topical administration to the scalp or skin which comprises a pharmaceutically acceptable oxalate of a Group Ia or IIa metal or ammonium oxalate or a tricologically active derivative thereof disposed in a topically applicable pharmaceutically acceptable carrier or diluent therefor, wherein the oxalate is derived from a vegetable extract, and is associated with mucilaginous carbohydrate derived from said vegetable extract. 2. A composition according to claim 1 wherein the pharmaceutically acceptable oxalate is an oxalate of a metal selected from calcium, barium, magnesium, lithium, sodium or potassium. 3. A composition according to claim 1 wherein the pharmaceutically acceptable carrier or diluent comprises at least one of a C.sub.3 to C.sub.4 lower alcohol and sterile water. 4. A composition according to claim 1 wherein the pharmaceutically acceptable carrier or diluent comprises a paraffin fraction and an emulsion base. 5. A composition according to claim 1 wherein the oxalate is calcium oxalate derived from an extract of squill. 6. A composition according to claim 1 further comprising an organic oxalate. 7. A method for enhancing the aesthetic appearance of the scalp or skin which comprises applying to the scalp or skin a composition which comprises a pharmaceutically acceptable oxalate of a Group Ia or IIa metal or ammonium oxalate or a tricologically active derivative thereof disposed in a topically applicable pharmaceutically acceptable carrier or diluent therefor. 8. A method for the restoration of hair loss which comprises applying topically to the scalp or skin a pharmaceutical composition comprising a pharmaceutically acceptable oxalate of a Group Ia or IIa metal or ammonium oxalate, or a tricologically active derivative thereof, disposed in a topically applicable pharmaceutically acceptable carrier or diluent therefor. 9. A method according to claim 8 wherein the pharmaceutically acceptable oxalate is an oxalate of a metal selected from calcium, barium, magnesium, lithium, sodium or potassium. 10. A method according to claim 8 wherein the pharmaceutically acceptable carrier or diluent comprises at least one of a C.sub.3 to C.sub.4 lower alcohol and sterile water. 11. A method according to claim 8 wherein the pharmaceutically acceptable carrier or diluent comprises a paraffin fraction and an emulsion base. 12. A method according to claim 8 wherein the oxalate is derived from a vegetable extract. 13. A method according to claim 8 wherein the oxalate is calcium oxalate derived from an extract of squill and wherein the calcium oxalate is additionally surrounded by a mucilaginous carbohydrate. 14. A method according to claim 8 wherein the composition further comprises an organic oxalate.

Details for Patent 5,639,459

Applicant	Tradename	Biologic Ingredient	Dosage Form	BLA	Approval Date	Patent No.	Expiredate
Merck Sharp & Dohme Corp.	ZOSTAVAX	zoster vaccine live	For Injection	125123	05/25/2006		2013-01-11