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Last Updated: April 24, 2024

Claims for Patent: 5,614,489

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Summary for Patent: 5,614,489

Title:	Method and composition for treating the skin
Abstract:	A cosmetic composition for treating skin includes by weight percent from 50-99.5% cosmetically acceptable vehicle for topical administration, 0.5-20% collagenase/elastase inhibitor, 0-10% moisturizer, 0-25% emollient, 0-10% humectant and 0-0.5% fragrance. A method for treating skin to reduce evidence of wrinkles and aging includes topically applying a cosmetic composition including a cosmetically effective amount of a collagenase/elastase inhibitor as an active ingredient.
Inventor(s):	Mohammadi; Fatemeh (Lexington, KY), Nosek; Dagmar (Lexington, KY)
Assignee:
Application Number:	08/450,430
Patent Claims:	1. A cosmetic composition for treating skin, comprising by weight percent substantially: 50-99.5% cosmetically acceptable vehicle for topical administration, said cosmetically acceptable vehicle being selected from a group consisting of water, wax, nonionic surfactant and mixtures thereof; 0. 5-20% collagenase/elastase inhibitor; 0-10% moisturizer; 0-25% emollient; 0-10% humectant; and 0-0.5% fragrance. 2. The cosmetic composition set forth in claim 1, wherein said collagenase/elastase inhibitor is selected from a group consisting of peptidyl carbamate, peptidyl thiocarbamate, hydroxamate, cephalosporin, sulfonate salt, and mixtures thereof. 3. The cosmetic composition set forth in claim 2, wherein said humectant/moisturizer is selected from a group consisting of polyethylene glycol, sorbitol, glycerin, propylene glycol monostearate and mixtures thereof. 4. The cosmetic composition set forth in claim 3, wherein said emollient is selected from a group consisting of synthetic oil, animal oil, vegetable oil, mineral oil and mixtures thereof. 5. The cosmetic composition set forth in claim 1, wherein said humectant/moisturizer is a polyethylene glycol. 6. The cosmetic composition set forth in claim 1, wherein said emollient is selected from a group consisting of synthetic oil, animal oil, vegetable oil, mineral oil and mixtures thereof. 7. A cosmetic composition for treating skin comprising by weight percent substantially: 50-99.5% cosmetically acceptable vehicle for topical administration, said cosmetically acceptable vehicle being selected from a group consisting of water, wax, nonionic surfactant and mixtures thereof; 0.5-20% collagenase/elastase inhibitor; and 0.1-25% of a moisturizer/emollient/humectant. 8. The cosmetic composition set forth in claim 7, wherein; said collagenase/elastase inhibitor is selected from a group consisting of peptidyl carbamate, peptidyl thiocarbamate, hydroxamate, cephalosporin, sulfonate salt, and mixtures thereof; and said moisturizer/emollient/humectant is selected from a group consisting of polyethylene glycol, propylene glycol monostearate, synthetic oil, animal oil, vegetable oil, mineral oil and mixtures thereof. 9. A method for treating skin to reduce evidence of wrinkles and aging, comprising: topically applying the cosmetic composition of claim 1. 10. A method for treating skin to reduce evidence of wrinkles and aging comprising: topically applying the cosmetic composition set forth in claim 1. 11. A method for treating skin to reduce evidence of wrinkles and aging comprising: topically applying the cosmetic composition set forth in claim 2. 12. A method for treating skin to reduce evidence of wrinkles and aging comprising: topically, applying the cosmetic composition set forth in claim 4. 13. A method for treating skin to reduce evidence of wrinkles and aging comprising: topically applying the cosmetic composition set forth in claim 7. 14. A method for treating skin to reduce evidence of wrinkles and aging comprising: topically applying the cosmetic composition set forth in claim 8.

Details for Patent 5,614,489

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Applicant	Tradename	Biologic Ingredient	Dosage Form	BLA	Approval Date	Patent No.	Expiredate
Smith & Nephew, Inc.	SANTYL	collagenase	Ointment	101995	06/04/1965	⤷ Try a Trial	2039-03-29
>Applicant	>Tradename	>Biologic Ingredient	>Dosage Form	>BLA	>Approval Date	>Patent No.	>Expiredate

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