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Last Updated: April 24, 2024

Claims for Patent: 5,589,171


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Summary for Patent: 5,589,171
Title: Treatment of Dupuytren\'s disease with collagenase
Abstract:Dupuytren\'s disease is treated by applying collagenase to the affected palmar fascia.
Inventor(s): Wegman; Thomas L. (North Merrick, NY)
Assignee: Advance Biofactures of Curacao (Brievengat, AN)
Application Number:08/294,097
Patent Claims:1. A method of treating an individual suffering from Dupuytren's disease which comprises applying an effective amount of collagenase to a fibrous of the affected fascia.

2. A method according to claim 1 wherein the amount of collagenase is within the range of about 100 to about 7,500 ABC units.

3. A method according to claim 1 wherein the collagenase is applied in a pharmaceutically acceptable carrier in a concentration of about 100 to about 10,000 ABC units collagenase per ml.

4. A method according to claim 3 wherein the concentration of collagenase is within the range of about 300 to about 700 ABC units per ml.

5. A method according to claim 3 wherein the carrier is aqueous.

6. A method according to claim 1 wherein the collagenase is applied to the fibrous cord.

7. A method according to claim 6 wherein collagenase in a liquid pharmaceutically acceptable carrier is injected into the fibrous cord.

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