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Last Updated: March 28, 2024

Claims for Patent: 5,532,158


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Summary for Patent: 5,532,158
Title: Interleukin-2 receptor deficient mammals
Abstract:A mouse lacking expression of a subunit of the IL-2 receptor in certain cells of the immune system is provided. Also provided are methods of using such mice.
Inventor(s): Suzuki; Haruhiko (Toronto, CA), Mak; Tak W. (Toronto, CA)
Assignee: Ontario Cancer Institute (Toronto, CA)
Application Number:08/326,896
Patent Claims:1. A DNA construct comprising a mouse IL-2R.beta. gene fragment spanning the region between the Bgl II site of intron 5 and the Nde I site at the 3' end of exon 7, wherein a neo gene cassette is inserted into the Aat II site of exon 6.

2. A mouse D3 embryonic stem cell line comprising the DNA construct of claim 1.

Details for Patent 5,532,158

Applicant Tradename Biologic Ingredient Dosage Form BLA Approval Date Patent No. Expiredate
Merck Sharp & Dohme Corp. INTRON A interferon alfa-2b For Injection 103132 06/04/1986 ⤷  Try a Trial 2039-02-26
Merck Sharp & Dohme Corp. INTRON A interferon alfa-2b For Injection 103132 ⤷  Try a Trial 2039-02-26
Merck Sharp & Dohme Corp. INTRON A interferon alfa-2b Injection 103132 ⤷  Try a Trial 2039-02-26
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Approval Date >Patent No. >Expiredate

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